If testosterone is a protective hormone, and nitric oxide is harmful and causes aging, how come testosterone increases nitric oxide?
"...at physiological concentrations T and DHT increase endothelial synthesis of NO. "
Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo. - PubMed - NCBI
I find the "nitric oxide theory of aging" very strange in general, since a lot of things that are considered Peaty increase (endothelial) nitric oxide.
"...at physiological concentrations T and DHT increase endothelial synthesis of NO. "
Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo. - PubMed - NCBI
I find the "nitric oxide theory of aging" very strange in general, since a lot of things that are considered Peaty increase (endothelial) nitric oxide.