Testimonial For Niacin - It Just Works

Discussion in 'Testimonials' started by redsun, Aug 22, 2019.

  1. OP
    redsun

    redsun Member

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    Generally high histamine is the main cause of problems in undermethylation. Betaine is made from choline. Some foods like wheat can provide betaine. Whether you are deficient in folate, B12, and choline you may need it. Choline can be easily obtained from plenty of eggs but problems with B12 absorption or low B12 intake is common and likewise can cause deficiency.
     
  2. BigChad

    BigChad Member

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    I got high histamine symptoms, although I was using niacinamide which is supposedly much more powerful of a methyl group depleter than niacin. Actually it was 80mg niacinamide and 40mg niacin a day.
    for some reason, apple cider vinegar, whether liquid or capsule form, causes severe stomach irritation/upper stomach pain for me. Magnesium malate, and malic acid also causes something similar. citric acid causes something similar if I do higher amounts of it. Anything more than 2 whole eggs, or egg whites in general, also cause a similar effect. whey protein, milk, lemonade/orange juice, oranges, meats, sodas with phosphoric acid, do not cause this sort of effect. I'm not sure why eggs would cause it, I think due to the sulfur in them.

    btw do you know if regular folic acid is fine to take, 400mcg every other day? I heard there are several issues with the folic acid form, yet also that methylated b vitamins should be avoided due to methylation speeding up the aging and cancer process.
    I have also heard regardless, creatine should be supplemented to reduce strain on the methylation cycle. Normally a lot of methylation is directed towards making creatine.
     
  3. Goobz

    Goobz Member

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    Niacin / nicotinamides depletion of the methyl donors in the blood seems to center around betaine, which is why it’s recommended to supplement along with B3. I don’t think methyl B12 would necessarily fill the gap in the same way.
     
  4. BigChad

    BigChad Member

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    True actually, if they are equivalent in terms of grams, b12 and folate are takin in just mch dosages while niacin, betaine and methionine are in mg or gram doses.
    Do you think 500mg betaine tmg per day is worth taking just as insurance. Whether you use niacin supplements or not
     
  5. Goobz

    Goobz Member

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    Well my post was directed towards protecting against potential problems caused by niacin, for which betaine/tmg seems the most useful. But if you’re not taking niacin, I’d say getting some tmg via diet (beets etc) and sufficient choline would probably be fine, since betaine/tmg is also a metabolite of choline. Just my own opinion and I’m no expert in this area
     
  6. OP
    redsun

    redsun Member

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    This is sort of an update. Been 2 weeks since I made this thread and probably almost a month since starting niacin experimentation. I have noticed if I were to not take niacin for a few days, by the 2nd day I start to get belching out of no where(even when I haven't eaten in the morning and just drank some juice or milk or nothing at all). Then I start back up and it goes away. I forgot how annoying digestive disturbances can be.

    I dont know if I already mentioned this but I attempted T3 tyronene awhile ago and it had similar effects of digestion, which was reduced symptoms of indigestion and digestive problems. Niacin seemingly does the same thing without me having to rely on T3. Better to replete a vitamin than use T3 to bandaid digestion. Nothing wrong with T3 of course but its always best to find the root issue if possible.
     
  7. charlie

    charlie The Law & Order Admin

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    Fantastic update. Thank you for sharing. :hattip
     
  8. BigChad

    BigChad Member

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    its fine to take 500mg betaine tmg alongside 100mg or 200mg niacin? or do they need to be taken separate
     
  9. Goobz

    Goobz Member

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    No idea but I’d imagine it’s fine, haven’t heard of anything about them interacting.
     
  10. Andy316

    Andy316 Member

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    Im a overmethylator and react badly to methyl donors (B6, B9, b12). I am Thinking of starting supplementing Betaine HCL with Pepsin (which is supposedly a methyl donor), wpuld supplementing niacin along with it cause less anxiety and other bad symptoms?
     
  11. BigChad

    BigChad Member

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    B6 is a phosphate thing?
    Also isnt the methyl in the methyl bs extremely small
     
  12. Andy316

    Andy316 Member

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    It could be but emotional turbulence I went through after supplementing Methyl B6/B9/B12 was extremely bad. I thought it was only the methyl B's but no, got the same reaction from normal B vits too. But im interested in doing a betaine HCL test to support my low stomach acid but also worried it may give me similar issues as the methyl B's so thinking maybe niacin with betaine HCL?? Your thoughts/experiences appreciated.
     
  13. OP
    redsun

    redsun Member

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    If you react badly, then you need unmethylated folate, folic acid. Usually overmethylators are good with B12 status, but folic acid is incredibly low. Methylfolate is usual recommendation but some people are so sensitive to methyl groups that folic acid is used. Folic acid is not enough to fix it, and lots of niacin lowers histamine over time and you end up with less in the end. Folic acid plus making sure to avoid excess B1, B2, B3, B6, vitamin C, calcium, and copper should allow the histamine levels to build up without being degraded and excreted too quickly. Calcium also reduces histamine by releasing it, thats why its recommended for histadelics(undermethylators) as even though it can exacerbate high histamine it will lower histamine in the long term. Zinc, vitamin E are also considered natural antihistamines if overdone.

    If you have low stomach acid I would supplement niacin though as you need it for acid production. Smaller doses(40mg/meal) work just fine.
     
  14. Vinny

    Vinny Member

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    Took today first time niacin 250 mg.
    I,m impressed!
    It,s the only supp from many i,ve tried so far, that I really feel it does something. This flush is very interesting sensation!
    Will be like that every time, @redsun, or the body will eventually get used to it? I mean, I don,t mind the reaction, but at work would may be a little embarasing...
    And, when I should start to increase the dosage?
     
  15. OP
    redsun

    redsun Member

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    For stomach acid production and overall gut health 250mg per meal is more than enough. The flush will get less over time if consistent. If you stop for a few days then start again the flush will be back. It will take some time for improvement in digestion but it's absolutely worth it. I am back down to 250mg as well, no longer do the higher doses as I dont think it makes a difference for stomach acid.
     
  16. charlie

    charlie The Law & Order Admin

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    Friendly reminder that even on the niacin forums they suggest starting very low, like 25mg and slowly working your way up.

    Hmm, I think I might be an overmethylator. Methyl form gives me anxiety. So your basically saying Folic acid needs to be brought in to balance things out?
     
  17. OP
    redsun

    redsun Member

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    According to pfeiffer, overmethylators have very low folic acid levels and high copper levels. Personally I dont know how convinced I am of about the copper as of late, but I do know, taking folic acid or methylfolate or anything else that is supposed to help overmethylators has tremendously helped my paranoia/anxiety/sleep issues and emotional bluntness(less blunt emotion). Funnily enough if you look on google one of the "side effects" of folate or folic acid is "depressed or overly excited".

    If an undermethylator takes folate, they can become depressed, if an overmethylator does, the opposite happens, excitement. I never got anxiety from methylfolate though I read some are sensitive to the methyl. Thats the best way to describe myself when I take lots of methylfolate(what Im currently taking now), makes me feel like a new person and its not an exaggeration. Gets rid of my strong emotional bluntness. I suppose I am not sensitive to methylfolate's methyl group then others, but you may be. Folic acid may work better for you as to not add more methyl.
     
  18. charlie

    charlie The Law & Order Admin

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    Thanks a bunch. I will give it a try.
     
  19. Andy316

    Andy316 Member

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    Thanks a lot Redsum, I'll buy the Niacin along with Betaine HCL and try each.

     
  20. Vinny

    Vinny Member

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    Thank you
     
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