T3, Methylene Blue and Prolactin

[maillol]

Peat city

(PDF) The regulation of adenohypophyseal prolactin secretion: Effect of triiodothyronine and methylene blue on estrogenized rat adenohypophysis

PDF | Estrogens and thyroid hormones contribute importantly to cell proliferation and tumor transformation in the pituitary gland. We found that... | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

 

[Grapelander]

Peat city

(PDF) The regulation of adenohypophyseal prolactin secretion: Effect of triiodothyronine and methylene blue on estrogenized rat adenohypophysis

PDF | Estrogens and thyroid hormones contribute importantly to cell proliferation and tumor transformation in the pituitary gland. We found that... | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

Thanks, good article.
Central dopaminergic and noradrenergic systems are the most important factors regulating pituitary growth and function. Recently nitric oxide (NO) was added to the list of the neurotransmitters and neuropeptides involved in the control of the anterior pituitary secretion. Our data suggest that estrogen-induced anterior pituitary growth is associated with decreased synthesis and metabolism of central catecholamines, reduction of adenohypophyseal beta-adrenergic receptors and increase of dopamine DA-2 receptors.
We found that the treatment with T3 or MB prevented both estrogen-induced catecholaminergic inhibition and dopamine DA-2 receptor increment in the anterior pituitary.

 

[maillol]

I probably should've included some juicy snippets in my original post to improve engagement. The whole thing is interesting though! Need to work on my click bait.