“In addition, in Silurana (Xenopus) tropicalis whole body larvae, T3 increases the expression of androgen-related genes, 5α-reductase type 1 (srd5alpha1) and ar (16). Therefore, the present study aimed to investigate whether TH- and sex steroid-related genes are also regulated by T3 in the brain of S. tropicalis tadpoles.”
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Regulation of Thyroid Hormone-, Oestrogen- and Androgen-Related Genes by Triiodothyronine in the Brain of Silurana tropicalis
Amphibian metamorphosis is an excellent example of hormone-dependent control of development. Thyroid hormones (THs) regulate almost all aspects of metamorphosis, including brain development and larval neuroendocrine function. Sex steroids are also important ...
