T1am, The Hormone Behind CFS?

[energyandstruct]

3-Iodothyronamine (T1AM): A New Player on the Thyroid Endocrine Team?

 

[energyandstruct]

bumping this thread, it's an interesting connection

 

[energyandstruct]

T1AM HYPOTHESIS OF ME/CFS

 

[mujuro]

That paper is very interesting. Looks promising. Just looking at how rapid and potent (and long lasting) the effects are on the rodents is pretty incredible:

Siberian hamsters (Phodopus sungorus), a hibernating rodent species, as well as mice, display a complete shift in respiratory quotient (RQ) from a normal, mixed carbohydrate and lipid value (0.90 for hamsters, 0.83 for mice) to an RQ value of approximately 0.7, indicating that a switch to pure lipid burning has occurred upon single-dose T1AM administration. Interestingly, this 0.7 RQ persisted in summer-acclimatized Siberian hamsters for at least 24 h after the T1AM injection, making this fueling shift the effect of longest duration yet to be observed with single-dose T1AM.