Szent-Györgi On Methylene Blue

[Travis]

Albert Szent-Györgi has written a few books on bioelectronics that are available online:

Bioenergetics
Introduction to Submolecular Biology
Bioelectronics: A study in cellular regulations, defense and cancer
The Living State: With Observations on Cancer

I have read one of them and am in the process of reading the rest. I came across this passage on methylene blue:

As I have shown in my earlier days,²⁴ one can knock out the whole respiratory chain by cyanide and then restore oxygen uptake by adding methylene blue which takes the whole electron transport over between dehydrogenases and O₂. This it can do, as pointed out by B. and A. Pullman,²⁵ because its k values are 0.398 and −0.354 respectively, almost ideally placed to make the dye into a good donor and acceptor.

²⁴A. Szent-Györgi, Biochem. Z. 150, 195, 1924

The first k value is related to the ionization potential, the measure of it's ability to donate electrons. The second k value is related to its ability to accept electrons.

 

[tca300]

Awesome! Thanks!

 

[encerent]

Time to take a drop

 

[Such_Saturation]

He had it all figured out

 

[Dragon]

nice find. :)

ps; as far as I can tell, none of those links will give the book/download without signing up

 

[Such_Saturation]

@Travis makes some of the best posts on this board (but this is just my opinion )

 

[lollipop]

@Travis makes some of the best posts on this board (but this is just my opinion )

+1

 

[Braveheart]

@Travis makes some of the best posts on this board (but this is just my opinion )

Yes!

 

[energyandstruct]

Albert Szent-Györgi has written a few books on bioelectronics that are available online:

Bioenergetics
Introduction to Submolecular Biology
Bioelectronics: A study in cellular regulations, defense and cancer
The Living State: With Observations on Cancer

I have read one of them and am in the process of reading the rest. I came across this passage on methylene blue:



The first k value is related to the ionization potential, the measure of it's ability to donate electrons. The second k value is related to its ability to accept electrons.

interesting