Kasra
Member
- Joined
- Jul 24, 2012
- Messages
- 53
Based on the abstract of this study, sucrose-fed rats had more abdominal fat, greater blood pressure, more free fatty acids, less testosterone, and less nitric oxide than controls.
Castration of these sucrose-fed rats lowered blood pressure, lowered free fatty acids, and increased nitric oxide.
Administration of testosterone to these castrated rats restored the increased blood pressure, increased FFAs, and decreased NO.
The most interesting bit was that sucrose lowered testosterone in the rats, since it's literally the only mention of an effect of dietary sucrose or fructose on testosterone that I've been able to find.
The weird part is that even though sucrose feeding lowered testosterone in the rats, further testosterone reduction (via castration) seemed to protect them from some of the harmful effects of sucrose feeding.
It seems that the harms of sugar intake were promoted by the presence of testosterone. The initial reduction of testosterone by sucrose feeding could be seen as a protective adaptation to mitigate the increased blood pressure, increased FFAs, etc.
Castration of these sucrose-fed rats lowered blood pressure, lowered free fatty acids, and increased nitric oxide.
Administration of testosterone to these castrated rats restored the increased blood pressure, increased FFAs, and decreased NO.
The most interesting bit was that sucrose lowered testosterone in the rats, since it's literally the only mention of an effect of dietary sucrose or fructose on testosterone that I've been able to find.
The weird part is that even though sucrose feeding lowered testosterone in the rats, further testosterone reduction (via castration) seemed to protect them from some of the harmful effects of sucrose feeding.
It seems that the harms of sugar intake were promoted by the presence of testosterone. The initial reduction of testosterone by sucrose feeding could be seen as a protective adaptation to mitigate the increased blood pressure, increased FFAs, etc.