Ssri (sertraline) And Coronary Artery Atherosclerosis

miko

Member
Joined
Mar 30, 2014
Messages
84
Age
36
Location
Poland
"Our findings suggest that long-term treatment with this drug promotes coronary artery atherosclerosis in non-human primates," Shively said. "This may be clinically significant for people because almost a quarter of middle-aged women in the United States take antidepressants, the most prescribed of which are SSRIs."

http://www.tasnimnews.com/english/Home/Single/703757

"Effects of Long-Term Sertraline Treatment and Depression on Coronary Artery Atherosclerosis in Premenopausal Female Primates"
 
Joined
Jun 21, 2017
Messages
104
"Our findings suggest that long-term treatment with this drug promotes coronary artery atherosclerosis in non-human primates," Shively said. "This may be clinically significant for people because almost a quarter of middle-aged women in the United States take antidepressants, the most prescribed of which are SSRIs."

Common Antidepressant Increased Coronary Atherosclerosis in Animal Model

"Effects of Long-Term Sertraline Treatment and Depression on Coronary Artery Atherosclerosis in Premenopausal Female Primates"

Was just researching this and read through the study above. It's worth noting that sertraline is commonly prescribed @ 50 - 100mg.

These monkeys received 20mg/kg @ about 4kg bodyweight each.

Conversion to humans gives a dose in the range of 560 - 800mg for an 80kg human. Pretty high. Low human doses may not present the same dangers
 
Similar threads
Thread starter Title Forum Replies Date
youngsinatra Weaning Off SSRI - Above All Reduce Stress? Mental Issues 15
Jwicks1995 SSRI withdrawal - Acetylcholine Cortisol, Serotonin, Histamine 7
P Hashimoto, metabolism and ssri Metabolism 2
Mito Why an antidepressant (SSRI) could be used to treat COVID-19 Miscellaneous Health Discussions 13
haidut Serotonin (and SSRI drugs) can cause anxiety and PTSD Scientific Studies 0
R Considering TRT As Last-Resort For Post-SSRI Sexual Dysfunction (PSSD) Ask For Help or Advice 27
haidut SSRI Drugs Increase Violent Behavior And Promote Recidivism Scientific Studies 0
haidut SSRI Drugs, Not Depression, Destroy Empathy Scientific Studies 0
fitnessgirl SSRI Increases Risk Of Pulmonary Hypertension In Newborns Scientific Studies 0
haidut SSRI Drugs Strikingly Toxic For Fetal Brain, May Cause Autism Scientific Studies 6
M Anti-Peat Felt Way Better On SSRI's Debate - Anti-Peat 27
A.R Do SSRI Drugs Usage Cause Feminisation In Men? Ask For Help or Advice 7
M SSRI Retards Growth, Makes Your Kids Short Health 0
L SSRI Impairs Minocyclins Antidepressive Action Articles & Scientific Studies 2
G Mirtazapine Or Other SSRI Make You Look Older(sagging And Sunken Face) Mental Issues 0
G Mirtazapine Or Other SSRI Make You Look Older(sagging And Sunken Face) Insomnia, Sleep Issues 16
G Mirtazapine Or Other SSRI Make You Look Older(sagging And Sunken Face) Cortisol, Serotonin, Histamine 0
B SSRI Withdrawal And Replacement Cortisol, Serotonin, Histamine 3
U Tappering Off SSRI Supplements, Pharmaceutical Drugs 14
haidut SSRI Drugs During Pregnancy Cause Child Autism, Antiserotonin Drugs Cure It Scientific Studies 3
haidut Antidepressants (SSRI) Make Females Unattractive, Provoke Male Aggression Scientific Studies 112
A Severe Cognitive Decline After SSRI Ask For Help or Advice 21
A A Way To Reverse Ssri Induced Excess Allopregnanolone? Ask For Help or Advice 6
haidut SSRI Drugs Such As Prozac (fluoxetine) Cause Antibiotic Resistance Scientific Studies 4
haidut Massive Study Says SSRI Drugs Are BOTH Ineffective And Dangerous Scientific Studies 15
haidut SSRI Drugs (Prozac) Worsen Prenatal Stress And May Contribute To Autism Scientific Studies 3
haidut Paternal Use Of SSRI Increase Risk For ADHD In His Children Scientific Studies 4
S HELP I WANT OFF OF SSRI’s HELP Cortisol, Serotonin, Histamine 7
P Paxil SSRI Withdrawl Sexual Dysfunction Health 13
biggirlkisss Interesting Study On Ssri Ask For Help or Advice 0
haidut SSRI Drugs May Cause Serious Lung Disease And Fibrosis Scientific Studies 14
haidut SSRI Make Organisms Demented, Violent & Homicidal, Even At Low Doses Scientific Studies 39
biggirlkisss Why Are Ssri's So Addictive? Ask For Help or Advice 6
J How Safe Is Pregnenolone? (For Healing SSRI Effects) Ask For Help or Advice 15
haidut SSRI Use In Children Dramatically Increases Risk Of Diabetes In Adulthood Scientific Studies 3
haidut SSRI / Serotonin Worsens Tinnitus Scientific Studies 13
haidut SSRI Drugs Linked To At Least 28 Murders, Including Mass Shootings In USA Scientific Studies 10
J Lab Results - 5+ Years Of Chronic Fatigue/insomnia + Brutal SSRI Withdrawals Blood Work, Labs 20
J Experiences Of Cypro After Long Term SSRI Use / Withdrawal? Cyproheptadine 5
logicalscout Post-SSRI Sleep Adaptations Discussion Thread Insomnia, Sleep Issues 7
haidut SSRI Drugs Impair Judgment, Wisdom, Understanding, Love And Empathy Scientific Studies 151
Serious Black If SSRI's Are Bad Then What Is The Alternative? Mental Issues 46
A How Fluoxetine (or Any SSRI) Affect Serotonin Levels In Synapses And Totaly? Cortisol, Serotonin, Histamine 1
ecstatichamster Antihistamines - Block Choline, Stop Working, SSRI-like, Anhedonia? Pharmaceutical Drugs 10
A Post-SSRI-Symptoms Mental Issues 9
Cymatic Post-SSRI Ask For Help or Advice 5
M Chronic Craniofacial Discomfort. Can Only Listen To Music If I'm On An SSRI. Need Supplement Advice Ask For Help or Advice 35
P Low Dose Dextromethorphan As An Alternative To SSRI's? Mental Issues 23
Brooks Esq. Idealabs Recommendation (Overcoming Post SSRI Sexual Dysfunction) Supplements, Pharmaceutical Drugs 47
M My Brief SSRI Experience Mental Issues 4

Similar threads

Top