Ssri (sertraline) And Coronary Artery Atherosclerosis

Discussion in 'Articles & Scientific Studies' started by miko, Apr 7, 2015.

  1. miko

    miko Member

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    "Our findings suggest that long-term treatment with this drug promotes coronary artery atherosclerosis in non-human primates," Shively said. "This may be clinically significant for people because almost a quarter of middle-aged women in the United States take antidepressants, the most prescribed of which are SSRIs."

    http://www.tasnimnews.com/english/Home/Single/703757

    "Effects of Long-Term Sertraline Treatment and Depression on Coronary Artery Atherosclerosis in Premenopausal Female Primates"
     
  2. Elderflower j58

    Elderflower j58 Member

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    I was prescribed this medicine 6 months ago and I have long standing extensive heart disease:eek:
     
  3. Johnson Bagfoot

    Johnson Bagfoot Member

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    Was just researching this and read through the study above. It's worth noting that sertraline is commonly prescribed @ 50 - 100mg.

    These monkeys received 20mg/kg @ about 4kg bodyweight each.

    Conversion to humans gives a dose in the range of 560 - 800mg for an 80kg human. Pretty high. Low human doses may not present the same dangers
     
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