SSRI Drugs May Cause Serious Lung Disease And Fibrosis

Discussion in 'Scientific Studies' started by haidut, Nov 28, 2017.

  1. haidut

    haidut Member

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    The study tries to downplay the risk by claiming that it is only relevant to "old, frail people". However, the specific lung issue linked to SSRI - bronchiectasis - is almost never found as an independent disease but rather almost always as a symptoms of cystic fibrosis. Given serotonin's primary role in development and progression of fibrosis I think the risks of SSRI drugs for ANY age group should immediately become apparent. As it is the case with so many other chronic and debilitating/lethal conditions lately, the rates of cystic fibrosis have been steadily increasing over the last 3 decades, which coincides almost perfectly with the prescription rate increase of SSRI drugs. Of course, instead of acknowledging the public health fiasco of the SSRI drugs, FDA and companies like Pfizer silently push anti-serotonin (5-HT2B) drugs like terguride through the system for quick approval as treatment for these serotonin-driven conditions. The system sells you both the poison and the remedy, and the pubic is oblivious.

    [Full text] The relationship of SSRI and SNRI usage with interstitial lung disease | CIA
    Bronchiectasis Study Links Antidepressants to the Disease in the Elderly
    "...Research has shown a jump in antidepressant use in the past several decades. Their use increased by 400 percent in the United States between the late 1990s and 2008, for example. The most commonly prescribed antidepressants are selective serotonin reuptake inhibitors, or SSRIs, and serotonin norepinephrine reuptake inhibitors, SNRIs. Both classes of drugs are associated with the development of interstitial lung diseases such as bronchiectasis. Researchers hypothesised that the link between antidepressants and the development of bronchiectasis and other lung diseases is more prevalent than previous studies have reported. Their study, published in the journal Clinical Interventions in Aging, is titled “The relationship of SSRI and SNRI usage with interstitial lung disease and bronchiectasis in an elderly population: a case–control study.

    "...The association between older people’s use of antidepressants and their developing a lung disease may be underreported, the researchers said. They think many doctors may be unaware of a lung disease because it has symptoms such as shortness of breath and fatigue that are common to this age group. The results suggest that doctors should prescribe antidepressants with care, minimizing the dose and period of treatment and considering alternative treatments where appropriate. Antidepressants “were significantly associated with the risk of ILD/B [bronchiectasis or another lung disease] in this elderly population,” the team wrote. “Because of their widespread usage, further studies should be done to validate these findings. Prescribers should cautiously monitor patients for development of insidious pulmonary [lung] symptoms when these drugs are used.”
     
  2. Soren

    Soren Member

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    Continually amazed by the depth of the corruption and the depth of the ignorance. It's as if they want to keep you sick unto death.

    Bizarrely I am still optimistic that truth will out and we will get a revolution in medicine. Technology is such a great equaliser that it is always getting more difficult for these monopolies to keep the truth hidden and to stop progress. Status quo's don't change, until they do.
     
  3. OP
    haidut

    haidut Member

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    And the strange thing is that most studies I have seen on SSRI explicitly say that doctors should minimize treatment period with SSRI to the minimum needed to achieve remission. Yet every doctor I have ever talked to says antidepressants have to be taken for life.
     
  4. Soren

    Soren Member

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    The majority of doctors to me in many ways resemble an indoctrinated group of people blindly following the dogma that the church of the pharmaceutical industry and the FDA set from on high. Only a very small percentage seem to have the the gumption to look outside the mainstream beliefs. Yet so much trust and faith is put in them. People have this conception in their mind that every doctor has been given some unique insight and knowledge into the human body that we "normal" people can't possibly understand so they blindly follow them and anyone who challenges the dogma is ridiculed and marginalised.

    On a side note do you see any movement away from SSRI drugs for the treatment of depression? Obviously terguride is a good sign that they are finally stumbling along the right path but that is not being marketed as a treatment for depression more the diseases that are caused by SSRIs and fibrosis. Perhaps the new drugs that are being researched for degenerative brain diseases (the ones similar to Allopregnanolone etc) will one day be marked as anti-depressants.
     
  5. OP
    haidut

    haidut Member

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    Here is something you might enjoy in regards to why people act that way with doctors:
    Human Pregnancy Length Controlled By Metabolism Speed, Not Pelvic Shape

    More recent antidepressants seem to focus more on epinephrine reuptake inhbition, which probably has an effect on dopamine as well. A few serotonin antagonists and dopamine agonists (pramipexole) are about to be approved for depression as well. I am very curious to see how the pharma will sell these new drugs while still keeping sales of the SSRI intact, or at least explain the inconsistencies.
     
  6. Soren

    Soren Member

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    Just read the post you linked. Couldn't agree more. Especially with the "something must be done" mentality. You see that in all levels of life, something happens and if someone suggests an idea to rectify it even if it is horrible people go along with it because they feel it is better than nothing. The fact that something is being done gives them comfort, people prefer to have an "expert" tell them what to do rather than discover for themselves.
     
  7. mujuro

    mujuro Member

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    My grandfather, 83, just came down with pneumonia. Scans revealed scarring on the lungs. His best guess was exposure to hay particles in a silo. He has been on escitalopram for 2 years now after the death of my grandmother. The doctors have him on steroids and an array of drugs to combat the side effects of other drugs. For 80 years of his life he didn't take a single drug.
     
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