Some Thoughts On Avocadoes

[Ukall]

Personally, that is why I'd rather let the body figure out how much PUFA it needs, synthesise it as needed, and then put it exactly where it wants the PUFA to be, rather than consume PUFAs and have them either circulating freely or potentially mobilised from storage.

Perhaps that can work if a body is working in its perfect conditions. For example, I'm remembering the story from Chris Masterjohn and his problem synthesizing cholesterol. If this happens due to a genetic problem, I wonder, regarding PUFAs, if something similar could happen too.

 

[tyw]

I don't see the correlation between those factors. Excess PUFAs inhibit Mead acid synthesis, which is what should be ocurring in ideal situation. (Considering excess >1% total calorie intake).

Btw, does mead acid anti-inflammatory effect work by immunosuppression?

Perhaps that can work if a body is working in its perfect conditions. For example, I'm remembering the story from Chris Masterjohn and his problem synthesizing cholesterol. If this happens due to a genetic problem, I wonder, regarding PUFAs, if something similar could happen too.

To Agent207's point, Mead acid is (20:3, n-9). It is a PUFA with 3 double bonds.

Because of the 3 double bonds, is it probably even more reactive than an n-6 fatty acids like Linoleic acid (18:2, n-6)

I speculate that Mead acid is a semi-functional replacement for DHA, with all the same effects -- if you look at DHA, you have 6 double bonds and a dual planar structure (see Michael Crawford's analysis). Mead acid, with the first double bond in the n-9 position, also seems to "curl up" and form a singular planar structure, basically exposing the same sort of the 3-double bond hexagonal carbon plane which DHA has two of.

The fact that the body decides to synthesis a specific type of PUFA with 3 double bonds when dietary PUFA is kept low, is indicative that there is a need for PUFAs in the body. (even if this need is minimal, and almost always exceeded by regular dietary consumption, it is still a hard requirement)

Then to Ukali's point, I cited studies in my DHA article about the observations that PUFA synthesis happens readily in humans. More likely than not, we are dealing with quite an old pathway (evolutionary speaking, even bacteria regulate the fatty acid double bond count on their membranes), and PUFA regulation is preserved as a means of defence against scarce situations.

.....

 

[PakPik]

I have HUGH success with OJ and milk diet

Same here! I must say my OJ is freshly squeezed, maybe some people fail with OJ if it's not fresh/great quality?

At first, no. But I had to get things worked out from years of high PUFA and high fat lowish carbs. It takes months for a metabolism to change direction even in a good way.

Avocado -- I ate 1 - 2 of them a day for a long time, maybe several years. And I ate a bag or two of pistachio nuts most days.

No wonder it takes some time to fix all this.

According to Peat, when people reach their 30s they have already accumulated such a huge amount of PUFA in their tissues so as to be considered basically PUFA poisoning. It's my experience that it takes very concrete and great dietary efforts to turn that body composition around. But it does pay, even if improvement comes little by little, but it's just too worth it in my experience and also from a theoretical point of view.

I loved nuts and avocadoes, ate big amounts daily, and I definitely had to completely cut them out. When and if my health stabilizes enough I may enjoy them on the rare occasion, but for now I stick to PUFA depletion S.O.S diet

the only reason I think we need *some* is that every root, tuber and vegetable has a little in it.

Yes, I also came to basically that conclusion. In fact, when I found out that most fruits have their share of PUFAs I was like, wait a minute. I for example was planning to eat a dozen or so guavas a day and that would give add so much PUFA as to affect my daily goals. I think, though, that everything points to PUFA being essential, and my take is we just need to be careful and try not too accumulate too much. Yet it's really hard to get a deficiency of them.

 

[michael94]

Same here! I must say my OJ is freshly squeezed, maybe some people fail with OJ if it's not fresh/great quality?

Look up how commercial OJ is processed

 

[Herbie]

Im wondering what you guys and girls think about this.

IMO

Condescending tone.

Anyone who says "you know" and "things like that" when lecturing is an idiot.

Wasn't clear or concise.

 

[damngoodcoffee]

I truly think this forum is blind leading the blind at times.

Some people are definitely a little bit too confident in telling others what's right. I have felt for a long time that some here tend to pretend to be more intelligent than they are about this physiology stuff.
I guess there's a pressure here to be really smart cause some really are, and Ray is.

I'm not. I'm just an average joe who was into feeling healthy and good, found Peat, and found that avoiding pufa, eating easily digestible carbs, eating more protein, using enough salt and drinking coffee makes me feel better than anything else i have stumbled across.

I think it's ok to try different things, report experimentations etc. but one shouldn't be so militant about what they think at any given moment. We all go back and forth with this diet stuff. Lord knows i have.

 

[schultz]

Some people are definitely a little bit too confident in telling others what's right. I have felt for a long time that some here tend to pretend to be more intelligent than they are about this physiology stuff.

This may be me lol. I'm not sure I have the best understanding of physiology/biochemistry, though usually I reply to correct something I think is being misinterpreted. If I don't have an answer I think is reasonable, I usually don't respond.

I'm trying my best is all!

As far as this "Ray said salmon and avocado was good" thing he said, he didn't say it quite like that. If we are going to use this as meaningful information maybe we should find the clip and then we can all listen to it. I remember that audio (though don't remember which podcast) and happen to think he was commenting on the macro ratio in the meal (rice, salmon for protein and avocado for fat). Eating a few pieces of sushi is not like eating a whole avocado. It's usually a little chunk or sliver in each, isn't it? Also, I don't think Ray wanted to spend time telling the lady every reason why her meal was not "optimal". It wasn't really the time for it, and it would have taken several hours to explain properly... If he had done it offhandedly like "Oh that meal sucks" the lady would have been confused as she probably was just some lady who doesn't follow Rays work. It would have been inappropriate.

I don't think it's fair to think "Ray says eating an avocado is hepatotoxic and then said that eating avocado is fine somewhere else! He is contradicting himself, now I can't trust what he says".

Let's be reasonable.

 

[Blossom]

I found a somewhat relevant post from the email depository,
Ray Peat Email Advice Depository

@Sheila wrote,
Question was regarding a 14yo boy born with a brain injury, with respect to what also might improve his brain function to enable talking. Recent introduction of 're-breathing' has reduced his spasmic movements, quietened his brain and may have improved his very dry skin. His temps are 36-37 but pulse very difficult to find. Also his brain is slowed (in a helpful way) when he eats (if rarely) nori rolls of salmon, avocado, sushi rice and seaweed surround. His general diet is excellent, digestible, low PUFA/gluten, sufficient etc. so the effect of this 'meal' is interesting. Slowing down "my brain firing too much" as he tells us, should help, does anything else occur to you [Dr Peat] that we could try?

Dr Peat kindly replies:

The dry skin and weak pulse suggest very low thyroid function. The salmon, avocado, and rice are a good balance of fat, protein, and carbohydrate; maybe fat cheese could be substituted for the salmon sometimes. Both sugar and fat stimulate the digestive system hormone that stimulates brain cell renewal. Progesterone helps to reduce tension and excitation, and protects nerves. Pregnenolone reduces stress, and protects nerves.

 

[johnwester130]

Here's what I don't like about this video and some of ray peat's writings,

they keep it vague. Purposefully non-forceful, non-authoritarian. As if he is hinting pufa is bad for me, and lets the reader work it out for themselves.

Anyway, avocadoes are vile and should be avoided.

 

[Stryker]

Here's what I don't like about this video and some of ray peat's writings,

they keep it vague. Purposefully non-forceful, non-authoritarian. As if he is hinting pufa is bad for me, and lets the reader work it out for themselves.

Anyway, avocadoes are vile and should be avoided.

Exactly , and thats why ive been living by peats writings for i think 5 years now..for the more informed people he explains the mechanistic functions of foods because every constituent of what you eat has a 'chemical' effect and for every one else he basically gives a rough idea of what you should be aiming to eat like .

There are people out there that if you give a recommendation that is to direct and goes against what they think they already know they will become defensive about it and you wont be able to help them.

The informed people will already know his stance on eating things like salmon and avocado and the reasoning behin dit , but if he said to the closed minded person "PUFA is poison so salmon and avocado are poison" the person would become offended and not take in any of it.

A lot of the time you have to be progressive in your advice.. eating salmon and avocado sushi is alot better than eating something from a fast food resturant and thats hes statement was quite vague "good balance of fat, protein, and carbohydrate; maybe fat cheese could be substituted for the salmon".

He is intelligent enough in knowing there is a way to adress a certain audience and a way not to.

Anyway thats my take on it, i could be completely wrong but its why i respect Ray so much because hes not another mindless zealot.

 

[Bahaa El wazzan]

I eat avocados only before sex

With cottage cheese and honey

2 hours before sex

You can have sex for 3 hours like a beast

I don't care too much what's healthy

I care what makes me happy, strong, looking good , staminated , and sure libido is libido

So
1 avocado
5 tablespoon honey
Cup of cottage cheese

And you will teach pornstarss how to have sex

 

[Bahaa El wazzan]

I was looking to this #cocktail


The saturated fat in cottage cheese
Will stabilise the unsaturated fat in avocados

And honey will replenish glycogen stores goddamit

And some will get to be saturated fatty acids

Live like a beast or die trying

 

[Bahaa El wazzan]

Let's get her

 

[Westside PUFAs]

I eat avocados only before sex

You can have sex for 3 hours like a beast

 

[Bahaa El wazzan]

Haha haha that how you look like after that combo

Dammit u got it u got it

 

[johnwester130]

I was looking to this #cocktail


The saturated fat in cottage cheese
Will stabilise the unsaturated fat in avocados

And honey will replenish glycogen stores goddamit

And some will get to be saturated fatty acids

Live like a beast or die trying

why even have the avocado ?

 

[Mito]

Study will pay people to eat avocados for 6 months - CNN

 

[Elephanto]

For people with intestinal barrier integrity issues, I think that a one-time serving of a small avocado could have net benefits on health as they increase mucin-producing genes which protects against intestinal permeability. Can be helpful after a night of heavy drinking for instance.

Influence of Dietary Avocado on Gut Health in Rats. - PubMed - NCBI

Intestinal mucins in health and disease. - PubMed - NCBI

A small one has about 14 grams of MUFA and 2.2 grams of PUFA. Probably not worth ever eating if you don't have issues with intestinal permeability but a single time serving could provide permanent benefits by restoring levels of mucins, provided you don't dissolve them again with alcohol or damage your gut with spicy foods, gluten etc.

 

[Sunrise]

For people with intestinal barrier integrity issues, I think that a one-time serving of a small avocado could have net benefits on health as they increase mucin-producing genes which protects against intestinal permeability. Can be helpful after a night of heavy drinking for instance.

Influence of Dietary Avocado on Gut Health in Rats. - PubMed - NCBI

Intestinal mucins in health and disease. - PubMed - NCBI

A small one has about 14 grams of MUFA and 2.2 grams of PUFA. Probably not worth ever eating if you don't have issues with intestinal permeability but a single time serving could provide permanent benefits by restoring levels of mucins, provided you don't dissolve them again with alcohol or damage your gut with spicy foods, gluten etc.

Any other way of replenishing mucins than with avocado?
There are studies that show lithium repair gut barrier. Maybe is also due to restoring mucins?

Back pain should be also a parameter as lower back pain is said to be greatly diminished by lithium. And gut linen health and back pain is correlated.

I have been in Mexico for the last months, country of fluoride ubiquity, water salt and agriculture use of that fluorinated water. Maybe that has screwed my gut barrier as I have a mysterious lower back pain when I wake up since I am here. But that same pain dissapeared one day after i ate one avocado (first in years of avoiding them ).
Some net sources claim potassium in avocado causes diminishing of inflammation. But the mucin and gut line restoration would be a more interesting factor. Nevertheless I don't want to become avocado dependent. That is why i ask for other mucin restoring ingredients or environmental factors.

One detail, the avocado I ate was with lemon red radish and onion, some kind of guacamole. And I wonder if the adding of lemon has some effect on the fat profile or other content of the avocado.