SolBan - Liquid Aspirin/Caffeine/Niacinamide Mix

[Pet Peeve]

Never seen anything to indicate that topical aspirin causes that. In fact, aspirin is sometimes used in anti-aging facial masks and has some remarkable effects, which have led Revlon to file a patent application for what is essentially my SolBan :)

They must be sued! They'll put all kinds of garbage in there like pufas and god knows what else... like the cheap progesterone creams. Not a bad publicity though :)

 

[marteagal]

[...] which have led Revlon to file a patent application for what is essentially my SolBan :)

Haha, that is pretty cool. But do you think this might cause you any trouble in the future?

 

[haidut]

Haha, that is pretty cool. But do you think this might cause you any trouble in the future?

I am hoping that their patent application may get dropped since there is already "prior work" (SolBan) in the public domain. But Revlon is a huge company, so they will probably find a way around it, or will simply intimidate me or find a way to make me change the ingredients. If I am lucky they will make a buy offer but I highly doubt they will.
What can I say, risks of the trade.

 

[dd99]

Haidut, you have posted before that two of the components of Solban (aspirin and niacinamide) have antifungal effects. Would Solban be useful as a topical antifungal, or could the alcohol be an issue?

 

[haidut]

Haidut, you have posted before that two of the components of Solban (aspirin and niacinamide) have antifungal effects. Would Solban be useful as a topical antifungal, or could the alcohol be an issue?

I think it may help. Aspirin is currently being investigated for approval as an anti-fungal drug, both topically and orally. Specifically, a recent study found aspirin to be effective even against the cryptococcus strain, which causes often fatal fungal meningitis in humans and is very difficult to treat with common anti-fungal drugs. The alcohol is not an issue, if anything it should help suppress fungal growth even more.

 

[dd99]

I think it may help. Aspirin is currently being investigated for approval as an anti-fungal drug, both topically and orally. Specifically, a recent study found aspirin to be effective even against the cryptococcus strain, which causes often fatal fungal meningitis in humans and is very difficult to treat with common anti-fungal drugs. The alcohol is not an issue, if anything it should help suppress fungal growth even more.

Great, thanks for the quick response.

 

[Ideonaut]

I have a new supplement (SolBan) for people interested in improving skin health or management of issues like hair loss, wrinkles, aging spots, cellulite, or simply protection from the sun.
It can be ordered from the links below:
http://mkt.com/idealabs-llc/solban-liquid (US orders)
EstroBan, Energin, StressNon, SolBan, Retinil, Oxidal For International Customers (International orders)

The supplement is for topical use only and consists of an ethanol solution containing niacinamide / nicotinamide, caffeine and aspirin. Each one of these ingredients has been shown in multiple human and animal experiments to be beneficial for skin health using topical administration. In addition, the combination of caffeine and niacinamide has been shown to work literally as a sunscreen so this could be an option for people who do not want to be exposed to the toxic excipients in most commercial products. While I do not claim that the product is effective for any medical condition, for information purposes I have listed a number of references below. These studies have looked at effectiveness and safety of each of the ingredients for specific conditions like UV skin damage, hair loss, photoaging, wrinkles, cellulite, skin cancer, dermatitis, acne, pruritis, eczema, psoriasis, etc.
Here is the official description I placed in the online stores together with the scientific references.
I would appreciate any thoughts and comments. Thanks in advance.
___________________________________________________________________________________
___________________________________________________________________________________

SolBan is a liquid mixture of niacinamide, caffeine, and aspirin. These ingredients have been shown in multiple human clinical trials (as well as animal studies) to have a highly protective effect on the skin against a number of harmful agents and processes. The list of harmful agents and processes includes sunlight (UV), metabolic disturbances, aging (wrinkles, cellulite), hormonal imbalance (acne, eczema, melasma), stress, polyunsaturated fats (PUFA), etc.
SolBan is available as a 20 % alcohol (ethanol) solution in a 2oz glass spray bottle. The product is intended and sanctioned for external use only.

Each bottle contains the following ingredients:
Niacinamide / Nicotinamide - 4% concentration (by volume)
Caffeine - 1% concentration (by volume)
Aspirin - 1% concentration (by volume)

The recommended method of administration is spraying the affected skin area until it has a thin layer of the solution and the letting it dry (without rubbing). The product can be used in place of a sunscreen solution (Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 ... - PubMed - NCBI) due to the UV-blocking properties of caffeine and niacinamide / nicotinamide.


1. NIACINAMIDE
Nicotinic acid/niacinamide and the skin. - PubMed - NCBI
Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. - PubMed - NCBI
A review of nicotinamide: treatment of skin diseases and potential side effects. - PubMed - NCBI
http://www.ncbi.nlm.nih.gov/pubmed/17147561
http://www.ncbi.nlm.nih.gov/pubmed/24635573
http://www.ncbi.nlm.nih.gov/pubmed/18492206

1.1 Hyperpigmentation and Skin Aging (niacinamide)
http://www.ncbi.nlm.nih.gov/pubmed/18492135
http://www.ncbi.nlm.nih.gov/pubmed/25399625
http://www.ncbi.nlm.nih.gov/pubmed/24993939
http://www.ncbi.nlm.nih.gov/pubmed/16029679
http://www.ncbi.nlm.nih.gov/pubmed/18047609
http://www.ncbi.nlm.nih.gov/pubmed/23355788
http://www.ncbi.nlm.nih.gov/pubmed/19845667
http://www.ncbi.nlm.nih.gov/pubmed/24033822
http://www.ncbi.nlm.nih.gov/pubmed/21822427
http://www.ncbi.nlm.nih.gov/pubmed/16766489
http://www.ncbi.nlm.nih.gov/pubmed/15807725

1.2 UV Damage (niacinamide)
http://www.ncbi.nlm.nih.gov/pubmed/12615518
http://www.ncbi.nlm.nih.gov/pubmed/19804594
http://www.ncbi.nlm.nih.gov/pubmed/22123419
http://www.ncbi.nlm.nih.gov/pubmed/24798949
http://www.ncbi.nlm.nih.gov/pubmed/22709272
http://www.ncbi.nlm.nih.gov/pubmed/23349012
http://www.ncbi.nlm.nih.gov/pubmed/23397947
http://www.ncbi.nlm.nih.gov/pubmed/24313740
http://www.ncbi.nlm.nih.gov/pubmed/20354654
http://www.ncbi.nlm.nih.gov/pubmed/20492562
http://www.ncbi.nlm.nih.gov/pubmed/19028705
http://www.ncbi.nlm.nih.gov/pubmed/17882270
http://www.ncbi.nlm.nih.gov/pubmed/15748504
http://www.ncbi.nlm.nih.gov/pubmed/9427980
http://www.ncbi.nlm.nih.gov/pubmed/10674181
http://www.ncbi.nlm.nih.gov/pubmed/2138506



2. CAFFEINE
http://www.ncbi.nlm.nih.gov/pubmed/17396054
http://www.ncbi.nlm.nih.gov/pubmed/18070215
http://www.ncbi.nlm.nih.gov/pubmed/10332073

2.1 Sunscreen effects (caffeine)
http://www.ncbi.nlm.nih.gov/pubmed/16864596

2.2 Skin cancer (caffeine)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129466/
http://www.ncbi.nlm.nih.gov/pubmed/25591953
http://www.ncbi.nlm.nih.gov/pubmed/21505179
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353410/
http://www.ncbi.nlm.nih.gov/pubmed/18179623
http://www.ncbi.nlm.nih.gov/pubmed/17388926
http://www.ncbi.nlm.nih.gov/pubmed/12570332
http://www.ncbi.nlm.nih.gov/pubmed/12392153

2.3 Other skin conditions (caffeine)
http://www.ncbi.nlm.nih.gov/pubmed/11712038
http://www.ncbi.nlm.nih.gov/pubmed/8740461
http://www.ncbi.nlm.nih.gov/pubmed/17214716
http://www.ncbi.nlm.nih.gov/pubmed/25382163
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500065/
http://www.ncbi.nlm.nih.gov/pubmed/24704471
http://www.ncbi.nlm.nih.gov/pubmed/21179241
http://www.ncbi.nlm.nih.gov/pubmed/16249145
http://www.ncbi.nlm.nih.gov/pubmed/9809669


3. ASPIRIN
http://www.ncbi.nlm.nih.gov/pubmed/20950260
http://www.ncbi.nlm.nih.gov/pubmed/16949225
http://www.ncbi.nlm.nih.gov/pubmed/8339418
http://www.ncbi.nlm.nih.gov/pubmed/12013195
http://www.ncbi.nlm.nih.gov/pubmed/9059677

I think I'll go get a bottle of vodka and add some niacinamide, aspirin, and caffeine. Any comments on whether that would work or how to figure how much of each ingredient to add?

 

[Jac]

Thanks Haidut! Have you ever considered making a simple skin moisturizer for the face? I haven't found anything that doesn't have at least one questionable ingredient. For example, from those niacinamide people I mentioned they sell a 4% niacinamide cream: http://acnessential.com/ But I don't think phenoxyethanol is ideal, and not sure what a couple of the other things even are.

Ingredients
Niacinamide, Purified water, Glycerol (Vegetable glycerine), Cetostearylalcohol, Caprylic triglycerides (derived from Coconut Oil), Coconut oil, Cetomacrogol, Phenoxyethanol, Hydroxy benzoates, Grapefruit seed extract (natural preservative).

Is there still a skin moisturiser/lotion in the works yet?

 

[haidut]

Is there still a skin moisturiser/lotion in the works yet?

Skin moisture depends primarily on metabolism and sebum production. I don't think the big industry of skin moisturizers actually accomplished anything positive other than a short-lived effects, which probably adds some toxins to your already high burden.

 

[mirc12354]

What about spraying the whole body about 30 minutes before going to the sauna in order to increase sweating?

 

[haidut]

What about spraying the whole body about 30 minutes before going to the sauna in order to increase sweating?

I don't know if it is safe to increase thermogenesis and sweating beyond what the sauna would cause. Some people have fainted or worse by doing that with drugs like DNP and caffeine.

 

[Peata]

I decided to start using this again, and just got my new order. I love the new, opaque spray bottle.

I have some questions on layering. I am trying to get a good skincare regimen down and thought after cleaning, I would apply Solban. Then apply an oil or oil mix. What I have put together is MCT oil, EVOO, and a bit of Progest E.

Does this sound effective to prevent skin aging and other issues?
And do you think the oil would dilute the Solban and break it down?

 

[haidut]

I decided to start using this again, and just got my new order. I love the new, opaque spray bottle.

I have some questions on layering. I am trying to get a good skincare regimen down and thought after cleaning, I would apply Solban. Then apply an oil or oil mix. What I have put together is MCT oil, EVOO, and a bit of Progest E.

Does this sound effective to prevent skin aging and other issues?
And do you think the oil would dilute the Solban and break it down?

I would wait for the Solban to dry out before applying an oily mix. SolBan has water and it will not go well with the oily mix, so its best to wait until it dries out. But in terms of effects, I think SolBan would be synergistic with the Progest-E. I would probably do SolBan in the morning and Progest-E in the evening as the progesterone can make you sleepy. Or you can do both at the same time but wait 5min after spraying SolBan.

 

[dfspcc20]

There was talk before about being able to order Solban in a larger bottle. Did anything ever come about from that? Getting ready to reorder soon.

 

[haidut]

There was talk before about being able to order Solban in a larger bottle. Did anything ever come about from that? Getting ready to reorder soon.

It really makes shipping very inconvenient and expensive as it makes the package bigger than the dimensions USPS likes most. Even if you use SolBan on your entire scalp once a day it should still last you more than a month. You only need to make think misty layer on the skin to get an effect. You don't need to drench yourself in the stuff.

 

[Peata]

I would wait for the Solban to dry out before applying an oily mix. SolBan has water and it will not go well with the oily mix, so its best to wait until it dries out. But in terms of effects, I think SolBan would be synergistic with the Progest-E. I would probably do SolBan in the morning and Progest-E in the evening as the progesterone can make you sleepy. Or you can do both at the same time but wait 5min after spraying SolBan.

OK, thank you.

Also, love the fast shipping. Yay USPS and Yay Idealabs!

 

[haidut]

OK, thank you.

Also, love the fast shipping. Yay USPS and Yay Idealabs!

Thanks! We do what we can and I also love USPS...on their good days

 

[dfspcc20]

It really makes shipping very inconvenient and expensive as it makes the package bigger than the dimensions USPS likes most. Even if you use SolBan on your entire scalp once a day it should still last you more than a month. You only need to make think misty layer on the skin to get an effect. You don't need to drench yourself in the stuff.

Makes sense. I was thinking more in terms of using it as a sun screen alternative for when we go on vacation.

 

[jdrop]

Solban has worked well to calm down the burn/itch of poison ivy. One spray on the area stops the issue for a few hours.

 

[haidut]

Solban has worked well to calm down the burn/itch of poison ivy. One spray on the area stops the issue for a few hours.

Perfect! What about insect bites?