Sodium Butyrate Reduces Brain Amyloid-β Levels and Improves Cognitive Memory Performance in an Alzheimer's Disease Transgenic Mouse Model at an Early

[David PS]

It is a mouse study but . . .

Sodium Butyrate Reduces Brain Amyloid-β Levels and Improves Cognitive Memory Performance in an Alzheimer's Disease Transgenic Mouse Model at an Early Disease Stage - PubMed

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and neuropathological features, including abnormal deposition of amyloid-β (Aβ) peptides, intracellular neurofibrillary tangles, and neuronal death. Identifying therapeutics which can reduce...

pubmed.ncbi.nlm.nih.gov

 

[aliml]

Consequently, in this study, we investigated the ability of the histone deacetylase inhibitor sodium butyrate (NaB) to attenuate memory deficits in the mouse model of AD following a 12-week feeding regimen.

Histone Deacetylase Inhibitors:​

• 3,3'-Diindolylmethane (cruciferous vegetables)
• β-Hydroxybutyric acid (β-hydroxybutyrate)
• Abexinostat
• Acetoacetic acid (acetoacetate)
• Allyl mercaptan (allium plants)
• Apicidin
• Belinostat
• Butyric acid (butyrate)
• Capsaicin
• Citarinostat
• Curcumin
• Diallyl disulfide (allium plants)
• Entinostat
• Fimepinostat
• Givinostat
• Indole-3-carbinol (cruciferous vegetables)
• Kevetrin
• Martinostat
• Mocetinostat
• Niacinamide
• Panobinostat
• Parthenolide (feverfew plant)
• Phenylbutyrate
• Pracinostat
• Quisinostat
• Resminostat
• Romidepsin
• Scriptaid
• Sodium butyrate
• Sodium oxybate (GHB sodium)
• Sodium phenylbutyrate
• Sodium valproate
• Sulforaphane (cruciferous vegetables)
• Trapoxin B
• Trichostatin A
• Tucidinostat
• Valnoctamide
• Valproic acid (valproate)
• Valproate pivoxil
• Valproate semisodium
• Valpromide

Histone deacetylase inhibitor - Wikipedia

en.wikipedia.org