SIBO Treatment Protocol

[Collden]

I'm not familiar with it, but there's '(5R)-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one'.

"Hypothyroidism and levothyroxine therapy are the most strongly associated to SIBO in our cohort. A case control study by Lauritano et al[27] has already revealed a high prevalence of SIBO in patients with autoimmune thyroiditis and hypothyroidism, but the influence of the autoimmune process was a questionable biasing factor. Multivariate analysis confirmed that levothyroxine therapy is a stronger predictor of SIBO than hypothyroidism. The underlying mechanism is unclear. One might speculate that hypothyroidism leads to hypomotility, but, surprisingly, levothyroxine therapy was even more associated to SIBO and not able to reverse the effect of hypothyroidism."​

@Collden @Wilfrid

Thanks, may have missed it but don't see how they define the hypothyroid non-levo population. I'd guess if they are not on any medication that they are probably less severely hypothyroid than the levothyroxine users to begin with which might explain the apparent worse outcomes with levo. Nevertheless we know that levo is often not used rationally and can suppress metabolism further when overdosed. Possible that the common advice to take levo on an empty stomach is also contributing to problems since its been noted to lead to abnormal hunger, stomach pain and weight gain.

My take-home message would be that hypothyroidism is bad for SIBO and getting it properly treated is important to resolve it.

 

[golder]

Apologies in advnace if it's a stupid question, but I've just had some Biosporin arrive. It appears that there's a small amount of compressed brown powder in a seperated compartment in the top of the ampule, in addition to the sweet liquid in the bottle. I've gone through 7+ Google pages and I can't find any info on it anywhere. I've never seen anything packaged in this way and I'm not sure why it's not already mixed, but I'm assuming you supposed to pour this compressed powder into the liquid and vigorously shake it?

 

[danishispsychic]

Flagyl and Keflex ? good luck with those. add a little Cipro in the mix if you want a messed up gut forever. no thanks

 

[Amazoniac]

- Small Intestinal Bacterial Overgrowth: A clinician's guide to evaluation and treatment | Sarah Cook (same as uploaded)