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- Aug 24, 2017
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I used to for increasing glucose oxidation, dopamine and CO2. I use it in doses of 300mg and rarely ever higher. Peat mentioned to you last time that B1 doesn't deplete manganese in reasonable doses. But it's always a good idea to take the other Bs if you're going to use very high B1 doses.mate if you get a chance could you discuss or maybe youve already discussed why do you use the high dose b1, is it due CO2 effects and acetozolamide effects... and whats been your experience and how do you get around the nutrient depletion, like wouldnt the megadoses of b1 potentially cause depletions in a bunch of other nutrients like other b vitamins... or manganese or something else