1. Spring Sale 10% Off @ LifeGivingStore.com Till June 10th With Coupon Code: SPRING2020
    Click Here!
    Dismiss Notice
  2. LifeGivingStore.com New Products List:
    Natural Dessicated Thyroid

    Magnesium Hydroxide

    Dismiss Notice

Should Peatarians Consider Antihistamines?

Discussion in 'Supplements' started by Ray-Z, Nov 7, 2012.

  1. Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    In several of his articles, Ray Peat suggests or implies that anthistamines may have beneficial effects. A few examples follow.

    (From "Serotonin, Depression, and Aggression: The Problem of Brain Energy.")

    (From "Not the 'Female Hormone,' But the Shock Hormone.")

    (From "Oils in Context.")

    (From "Preventing and Treating Cancer With Progesterone.")

    (From "Autonomic Systems.")

    If you have used antihistamines, it would be great to hear about your experiences -- positive and negative -- with them. Do they have undesirable side effects or ingredients? Are some better than others? Are there better ways than drugs to achieve the benefits of antihistamines? Under what circumstances, if any, do you think Peatarians should consider using them?

    Thanks in advance for your thoughts.
     
  2. kettlebell

    kettlebell Member

    Joined:
    Oct 14, 2012
    Messages:
    417
    Location:
    UK
    Excellent topic! I look forward to the responses. I am totally uneducated in regards to this so can't comment.

    I am going to experiment with some, one a day or something like that and see if it has any effect.
     
  3. charlie

    charlie The Law & Order Admin

    Joined:
    Jan 4, 2012
    Messages:
    11,271
    Gender:
    Male
    Location:
    USA
  4. OP
    Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    Thanks, kettlebell and Charlie, for your encouragement.

    I'll briefly describe my own experience. I have had allergies (stuffy nose, itchy skin, bad reactions to many common foods) almost my entire life and have used quite a few different antihistamines, most of which I do not remember well. I can recall my experiences with benadryl (non-prescription) and allegra (prescription), which I took at different times, pre-Peat.

    Benadryl (diphenhydramine) did not seem to do anything besides knock me out. Because I could not take benadryl during the day time, and was always asleep or groggy when using it, it is conceivable that it had some mildly beneficial effects that I did not notice.

    In low to moderate doses, allegra (fexofenadine) did not seem to do anything for me. The "24 hour" version of allegra (180 mg, I think) offered some -- though hardly complete -- relief from food allergies and seasonal nasal congestion. No noticeable side effects. All in all, not a great drug, but not worthless, either. I quit allegra a few years ago when I started becoming skeptical of the medical establishment. Was allegra the one "good" medication my MDs prescribed for me?

    I'm curious about others' experiences...

    EDIT: I should add that I did not noice any general metabolic or anti-inflammatory benefits from any antihistamine, but keep in mind that at the time, I was THE ANTI-PEAT -- a sick bundle of wheat, stress, and PUFA.
     
  5. PeatFeat

    PeatFeat Member

    Joined:
    Oct 31, 2012
    Messages:
    55
    I have taken both Zyrtec and Claritin. I think they help with food allergies but not any major difference. I have been weary of taking any kind of medication, like it would weaken my system?. I have noticed Peat's comments on them and was already planning on taking 5-10mg at night (zyrtec makes me drowsy) after I had some allergy testing done. I will let you guys know if I notice anything.
     
  6. norxgirl

    norxgirl Member

    Joined:
    Oct 1, 2012
    Messages:
    42
    (May be duplicate post)

    Started Benadryl again after reading that antihistamines are antiestrogenic. They are helping me get to sleep.

    I did use a few times when working nights, but had to stop because they made me so drowsy at work the next night. I am now taking the same or stronger doses, and I really feel fine the next day....no grogginess. I am assuming I have a lot more estrogen dominance today than I did when using antihistamines before.

    Claritin also makes me drowsy, so would not take during the day.

    Back in May of this year, before starting on NDT, I had terribly swollen nasal passages almost all the time. It was awful. They are better most of the time these days/nights.
     
  7. chris

    chris Member

    Joined:
    Oct 8, 2012
    Messages:
    437
    Location:
    UK
    I used certrizine hydrochloride for months at a time during hayfever season, with great benefit. I used piriton for a while but it made me too drowsy. Not used any for a while as my hayfever seems to be 99% gone.
     
  8. OP
    Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    Thanks, PeatFeat. Would be great to hear what you find out.


    Thanks for the info, norxgirl. Do you think that the benadryl is helping with your nose, or are other changes, such as the NDT, more responsible?

    (Note: cetirizine hydrochloride = zyrtec.)

    Thanks for the info, Chris. Glad to have a success story.
     
  9. norxgirl

    norxgirl Member

    Joined:
    Oct 1, 2012
    Messages:
    42
    Ray-Z wrote:

    "Thanks for the info, norxgirl. Do you think that the benadryl is helping with your nose, or are other changes, such as the NDT, more responsible?"

    Hi Ray-Z,

    I am thinking probably the NDT, and Progest-E, yada yada. I also started a Now Brand gel multivitamin and some other supps, so the Vit. A may be helping with liver stuff. The Benadryl does dry me out. But I noticed the nasal stuffiness pretty much cleared up most of the time before I started the Benadryl back. I was a royal mess 6-7 months ago, barely functional.....pitiful, pitiful. I could hardly put two thoughts together. I was so bumfuzzled and frustrated at the swollen nasal passages and having to breathe through my mouth all the time. I was still working, very part-time, and did not know if I was allergic to the nasty house I was in, or my home, or what. I did not know if it was my stuffy nose that was contributing to my insomnia, or vice verse. It is amazing that I feel I may be partly back in the game of life. I think pregnenolone is also helping a lot.
     
  10. charlie

    charlie The Law & Order Admin

    Joined:
    Jan 4, 2012
    Messages:
    11,271
    Gender:
    Male
    Location:
    USA

    :dancenanner
     
  11. OP
    Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    norxgirl: Sounds like you averted a true disaster. Congratulations. I hope that in time you're able to move from "partly back in the game of life" to "fully back." And thanks for the info re your experiences.
     
  12. OP
    Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    For the last week or so, I've been experimenting with allegra (fexofenadine) and benadryl (diphenhydramine), two common antihistamines. I typically take one "24 hour" allegra tablet (180 mg) a few hours before bedtime and 1-2 benadryl (25 mg each) about 30-60 minutes before bedtime.

    My nose still gets a bit congested, but with the antihistamines, I have significantly less difficulty breathing through my nose at night -- a big benefit. :mrgreen:

    As discussed elsewhere, I have been highly allergic to dairy for many years. Yesterday and today, I tried eating some Peat-friendly ice cream, and had a milder reaction than usual, probably at least in part due to the antihistamines.

    The benadryl tends to make me sleep later and feel groggy when I awaken. I'm not thrilled by these effects, but they might be helpful to people who awaken too early. :2cents

    A possible drawback of these antihistamines: The lists of "inactive ingredients" aren't pretty. :eek:
     
  13. charlie

    charlie The Law & Order Admin

    Joined:
    Jan 4, 2012
    Messages:
    11,271
    Gender:
    Male
    Location:
    USA
    Them darn nefarious excipients.

    Ray-Z did you ever try that ricotta cheese recipe that I made from Ark's website?
     
  14. Birdie

    Birdie Member

    Joined:
    Aug 10, 2012
    Messages:
    1,885
    Gender:
    Female
    Location:
    USA
    I've tried benedryl. It gives me rapid hert beat and extreme dry mouth. I'm concerned that the dry mouth could lead to cavities. No saliva washing the mouth during the night.. Also it makes me drowsy next day.

    I found some gel caps with better ingredients but they can't be cut for a smaller dose. So, at times I use a half a tab in spite of awful ingredients.

    I think benedryl is good if you can tolerate it. My husband uses it intermittently. He complains of drowsiness but doesn't experience the rapid heart beat. He also uses loratadine/flatiron and ceterizine/zyrtec at times. He takes breaks from all of them.

    I do remember Ray's mentioning benedryl use but does he think highly of the other ones? Anybody remember? It seems he liked another one too.... .?
     
  15. Birdie

    Birdie Member

    Joined:
    Aug 10, 2012
    Messages:
    1,885
    Gender:
    Female
    Location:
    USA
    Clariton not flatiron. Thanks spellcheck.
     
  16. OP
    Ray-Z

    Ray-Z Member

    Joined:
    Oct 16, 2012
    Messages:
    321
    Charlie:

    I've been at a location with very spotty internet connectivity; sorry for the delayed response.

    You're right, I should try your recipe at some point. About 6 weeks ago, I bought ricotta that looked very Peat-friendly (no enzymes or "vegetable rennet"), and it constipated me pretty badly. I fared better with the ice cream a few days ago. I will try cheese again after I've given my gut a few weeks of vacation from dairy. :lol:

    Birdie:

    The rapid heart beat and dry mouth are interesting; I can't say I've experienced those side effects, but I can see why they might make you wary. Thanks for the tip about benadryl gel caps with better ingredients. :D

    You make a good point: While I've seen Ray Peat praise antihistamines (as in the quotes I listed at the beginning of this thread), I don't know which ones he likes best or whether there are any he considers unsafe. So I should emphasize that my own experiments with allegra are based upon his observations about antihistamines in general rather than any positive statements he's made about allegra in particular.
     
  17. Birdie

    Birdie Member

    Joined:
    Aug 10, 2012
    Messages:
    1,885
    Gender:
    Female
    Location:
    USA
    I have a benadryl update. Since somebody asked a question about antihistamines in the RP Fans group, I decided to try again. I'm taking 1/3 tablet. (25 mg tab).
    The first couple of nights I experienced dry mouth again as usual. But, after a week that isn't happening. And no rapid heart beat at this dose.

    I could try upping to 1/2 tab. In this way, could slowly increase the dose.
     
  18. shaadoe

    shaadoe Member

    Joined:
    Sep 20, 2012
    Messages:
    23
    I feel extremely drowsy after taking benadryl so I will take it at night because it knocks me out. Zyrtec does not have the same drowsiness symtoms and I actually feel pretty good after taking it.
     
  19. Mastemah

    Mastemah Member

    Joined:
    Jul 23, 2012
    Messages:
    92
    He likes doxylamine succinate. In addition to its anti histamine effects when combined w B6 it helps morning sickness. Why is this cool? The theory on morning sickness is that it's too much serotonin in the small intestine causing spasms :)
     
  20. HDD

    HDD Member

    Joined:
    Nov 1, 2012
    Messages:
    2,013
    It should help other serotonin problems, too, right?
     
Loading...