"Serotonin deficiency may not cause depression after all"

TheCanadian

Member
Joined
Dec 18, 2013
Messages
7
Re: "Serotonin deficiency may not cause depression after all

Well its been known for a while that SSRI usually dont work much in many cases and hypothyroidism is to blame for it ( sorry for busting ur topic it seemed appropriate )
 

Mittir

Member
Joined
Feb 20, 2013
Messages
2,034
Re: "Serotonin deficiency may not cause depression after all

TheCanadian said:
Well its been known for a while that SSRI usually dont work much in many cases and hypothyroidism is to blame for it ( sorry for busting ur topic it seemed appropriate )

You have completely missed the purpose of this post.
This is Ray Peat forum and it is well known here that low serotonin is not
the cause of depression and thyroid health is the central issue.
The poster is simply making a point that
mainstream science is slowly catching onto this idea.
 

Agent207

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Joined
Jul 3, 2015
Messages
618
Charlie said:
post 34927 New research may lead to a more direct and effective treatment than common SSRIs.

Click here for article

If you read the study closely, you will see it suggests a new mechanism by which depression may be caused, but it never negates the serotonin activity - depression link. It just says that the root may not be the neurotransmitter (un)availability issue, but rather the lack of synapses or inability to create new ones for it to act. In which case SSRIs would be obviously useless.

The model big farma promotes its just a bad patch looking for profits, worsening the condition in lots of cases, and with detrimental side effects in others. But aside of this, serotonin activity/imbalance -as well other neurotransmitters- does play a rol for sure in depression, both if too high or too low. Determining when it happens and how to fix is the big question.
 
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Nicholas

Member
Joined
Apr 25, 2015
Messages
666
Agent207 said:
post 111672
Charlie said:
post 34927 New research may lead to a more direct and effective treatment than common SSRIs.

Click here for article

If you read the study closely, you will see it suggests a new mechanism by which depression may be caused, but it never negates the serotonin activity - depression link. It just says that the root may not be the neurotransmitter (un)availability issue, but rather the lack of synapses or inability to create new ones for it to act. In which case SSRIs would be obviously useless.

The model big farma promotes its just a bad patch looking for profits, worsening the condition in lots of cases, and with detrimental side effects in others. But aside of this, serotonin activity/imbalance -as well other neurotransmitters- does play a rol for sure in depression, both if too high or too low. Determining when it happens and how to fix is the big question.

thanks!
 
Last edited by a moderator:
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