Sea Cucumber Extract Frondoside A Inhibits Prostaglandin Formation

Discussion in 'Articles & Scientific Studies' started by EndAllDisease, Jan 30, 2016.

  1. EndAllDisease

    EndAllDisease Member

    Jul 6, 2014

    Sea cucumbers are squishy, boneless saltwater creatures found on the bottom of oceans worldwide, whose bodies are shaped like cucumbers and wrapped in a soft, leather-like casing. A study shows that one of the many anti-cancer substances found in the sea cucumber works by antagonizing the EP2 and EP4 receptors.

    "We now show that Frondoside A antagonizes the prostaglandin E receptors EP2 and EP4. These studies identify a new function for an agent with known antitumor activity, and show that the antimetastatic activity may be due in part to a novel mechanism of action. These studies add to the growing body of evidence that Frondoside A may be a promising new agent with potential to treat cancer and may also represent a potential new modality to antagonize EP4."

    Date: 2012 | Location: University of Maryland Greenebaum Cancer Center, Baltimore, MD, USA