Scientists Map How Immune System Fights COVID-19

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Coronavirus: Australian scientists map how immune system fights virus
“Scientists in Australia say they have identified how the body's immune system fights the Covid-19 virus.

Their research, published in Nature Medicine journal on Tuesday, shows people are recovering from the new virus like they would from the flu.

Determining which immune cells are appearing should also help with vaccine development, experts say.

Globally, authorities have confirmed more than 160,000 cases of the coronavirus and about 6,500 deaths.

"This [discovery] is important because it is the first time where we are really understanding how our immune system fights novel coronavirus," said study co-author Prof Katherine Kedzierska.

The research by Melbourne's Peter Doherty Institute for Infection and Immunity has been praised by other experts, with one calling it "a breakthrough".

What has been found?
Many people have recovered from Covid-19, meaning it was already known that the immune system can successfully fight the virus.

But for the first time, the research identified four types of immune cells which presented to fight Covid-19.

They were observed by tracking a patient who had a mild-to-moderate case of the virus and no previous health issues.”
Scientists map how immune system fights virus

“We report the kinetics of immune responses in relation to clinical and virological features of a patient with mild-to-moderate coronavirus disease 2019 (COVID-19) that required hospitalization. Increased antibody-secreting cells (ASCs), follicular helper T cells (TFH cells), activated CD4+ T cells and CD8+ T cells and immunoglobulin M (IgM) and IgG antibodies that bound the COVID-19-causing coronavirus SARS-CoV-2 were detected in blood before symptomatic recovery. These immunological changes persisted for at least 7 d following full resolution of symptoms.”
Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
 
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