SAM-E & TMG Question

[member 6316]

Overmethylators are usually high in copper/estrogen. This is what causes the overmethylation so u take things that lower copper. Zinc is a good one, magnesium is good, vitamin c, p5p in low doses.

Would start with something like:

2x20mg zinc
1gr vitamin c
20mg p5p
800mg magnesium

See how u feel. If you dont feel good on this i would drop the p5p since it makes some people better and some people worse. Zinc vitamin c and magnesium are definitely good.

so some vitamins that i can get from food is gonna fix it? sounds too good to be true or should i say too easy to be true

 

[Amber]

Yes. Overmethylation is simply a copper toxicity problem. Vitamin c, zinc and p5p are antagonistic to copper. Magnesium calms u down and lowers stress.

 

[member 6316]

Yes. Overmethylation is simply a copper toxicity problem. Vitamin c, zinc and p5p are antagonistic to copper. Magnesium calms u down and lowers stress.

so anyone with a bad diet can have this or is it genetics?

 

[Amber]

so anyone with a bad diet can have this or is it genetics?

Both. Excess copper stimulates high neurotransmitter production and thats all there is to overmethylation. Excess neurotransmitters cause those symptoms. There are people with genetic defects, definitely. Lots of different mutations, but you can't find that out without bloodtests.

Im not convinced that over/undermethylation are real conditions. For me, either someone has a mutation that impairs the methylation or someone has certain nutrient deficiencies that cause the symptoms. Like in the case of overmethylation, its specific nutrient deficiencies (zinc, vitamin c, b6/p5p, sometimes manganese) that cause another nutrient (copper) to overaccumulate and disrupt proper metabolism.

 

[member 6316]

Both. Excess copper stimulates high neurotransmitter production and thats all there is to overmethylation. Excess neurotransmitters cause those symptoms. There are people with genetic defects, definitely. Lots of different mutations, but you can't find that out without bloodtests.

Im not convinced that over/undermethylation are real conditions. For me, either someone has a mutation that impairs the methylation or someone has certain nutrient deficiencies that cause the symptoms. Like in the case of overmethylation, its specific nutrient deficiencies (zinc, vitamin c, b6/p5p, sometimes manganese) that cause another nutrient (copper) to overaccumulate and disrupt proper metabolism.

alright.. im gonna try it but i highly doubt it will work . so just those 4 supplements? Why sometimes manganese? manganese does something else?

 

[Amber]

Manganese lowers copper in the liver, but i'd try to get manganese from food.

If you want, you can raise the dose of the supplements when you feel like its working.

 

[member 6316]

Manganese lowers copper in the liver, but i'd try to get manganese from food.

If you want, you can raise the dose of the supplements when you feel like its working.

i have a supplement with all these 4 ingredients but it also has a lot of other stuff to here are the ingredients:https://d2wu4z6q8vok4i.cloudfront.net/media/contenttype/Primal_MasterFormula_Facts.jpg anyway I will be getting: 20mg p5p,
30mg zinc,
400 mg magnesium &
1g vitamin c.....

is that enough? how long do i need to take it

(EDIT) just realised this has some other ingredients that are bad for me,, tmg, copper etc

 

[Amber]

Taking them all together doesn't work.

Take magnesium in doses of 400mg together with the p5p

Take zinc before going to bed

Take vitamin c away from all other vitamins

Do not eat any calcium rich foods when taking any of these vitamins it will block their absorption.

 

[Dave Clark]

Depends on what scares you more, methionine or homocysteine. If you are an undermethylator and have high homocysteine levels, TMG is effective at reducing those levels (homocysteine being implicated in cardiovascular disease).

 

[Mito]

when someone has confirmed undermethylation

How would you confirm undermethylation?

 

[Amber]

Methylation Profile; plasma | Doctor's Data

DNA Methylation Whole Blood | Doctor's Data

 

[member 6316]

Amber do you know if high levels of homocystein causes overproduction of serotonin?

 

[damngoodcoffee]

Dr. Wilson also has an article about elves.

 

[Amber]

Amber do you know if high levels of homocystein causes overproduction of serotonin?

Im not sure but i don't think so

 

[lollipop]

Dr. Wilson also has an article about elves.

??? What do you mean @damngoodcoffee?

 

[damngoodcoffee]

??? What do you mean @damngoodcoffee?

I remember Dr. Wilson pushing TMG. And the guy is nuts.

 

[lollipop]

I remember Dr. Wilson pushing TMG. And the guy is nuts.

Oh - lol. I agree, can't read his stuff

 

[member 6316]

are there any sources on taking vitamin c, zinc etc for overmethytlation?i wanna know where you got that from. @Amber

 

[Amber]

http://www.biobalance.org.au/_downloads/targeted-nutritional-treatment-of-mental-illness.pdf

Mostly this, and from my study. My study is about health/the body/brain and stuff like that. Also, logical thinking since overmethylation is copper excess, and those vitamins antagonize copper.

 

[member 6316]

http://www.biobalance.org.au/_downloads/targeted-nutritional-treatment-of-mental-illness.pdf

Mostly this, and from my study. My study is about health/the body/brain and stuff like that. Also, logical thinking since overmethylation is copper excess, and those vitamins antagonize copper.

what about vit e ,vitamin b6, niacin, folate and b12 those not important??