Risk of Intracranial Haemorrhage in Antidepressant Users With Concurrent Use of Non-steroidal Anti-inflammatory Drugs: Nationwide Propensity Score Matched Study
Conclusion
The addition of NSAIDs to antidepressant treatment increased the risk of intracranial haemorrhage within 30 days of the combination starting, especially in men. This result adds to evidence confirming the increase of risk with combination use of antidepressants and NSAIDs. Special attention is needed when patients use both these drugs together.
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