Risk of cancer in patients with glaucoma: A nationwide population-based cohort study

[Trullo]

Abstract​

To compare the risk of cancer development between patients with glaucoma and those without, we conducted a nationwide population-based cohort study using the Korean National Health Insurance Database. Individuals with diagnosis of glaucoma between 2007 and 2016 were identified, and controls were 1:1 matched based on age and sex. We calculated the incidence rates(IR) and hazard ratios(HR) before and after adjusting for age, gender, diabetes, smoking history, and body mass index. A total of 107,536 individuals with glaucoma and the same number of individuals without glaucoma were included. The IR of overall cancer were 12.23 and 11.62 per 1,000 individuals in the glaucoma and control groups, respectively. The HR of overall cancer was significantly higher in the glaucoma group before(HR: 1.053) and after adjusting for confounding factors(adjusted HR: 1.049) compared to that in the control group. The risk of overall cancer and specific cancers varied depending on gender and age groups, and the association was stronger in women and those under 65 years of age. Our study revealed that individuals with glaucoma showed higher risk of overall cancer and higher risk of specific cancers than those without glaucoma.

Risk of cancer in patients with glaucoma: A nationwide population-based cohort study - Scientific Reports

To compare the risk of cancer development between patients with glaucoma and those without, we conducted a nationwide population-based cohort study using the Korean National Health Insurance Database. Individuals with diagnosis of glaucoma between 2007 and 2016 were identified, and controls were...

www.nature.com

 

[Rinse & rePeat]

Abstract​

To compare the risk of cancer development between patients with glaucoma and those without, we conducted a nationwide population-based cohort study using the Korean National Health Insurance Database. Individuals with diagnosis of glaucoma between 2007 and 2016 were identified, and controls were 1:1 matched based on age and sex. We calculated the incidence rates(IR) and hazard ratios(HR) before and after adjusting for age, gender, diabetes, smoking history, and body mass index. A total of 107,536 individuals with glaucoma and the same number of individuals without glaucoma were included. The IR of overall cancer were 12.23 and 11.62 per 1,000 individuals in the glaucoma and control groups, respectively. The HR of overall cancer was significantly higher in the glaucoma group before(HR: 1.053) and after adjusting for confounding factors(adjusted HR: 1.049) compared to that in the control group. The risk of overall cancer and specific cancers varied depending on gender and age groups, and the association was stronger in women and those under 65 years of age. Our study revealed that individuals with glaucoma showed higher risk of overall cancer and higher risk of specific cancers than those without glaucoma.

Risk of cancer in patients with glaucoma: A nationwide population-based cohort study - Scientific Reports

To compare the risk of cancer development between patients with glaucoma and those without, we conducted a nationwide population-based cohort study using the Korean National Health Insurance Database. Individuals with diagnosis of glaucoma between 2007 and 2016 were identified, and controls were...

www.nature.com

This is interesting because when I think of all the people I know who have had cataract surgery they are also dealing with some kind of cancer hmmmm…..

 

[Trullo]

This is interesting because when I think of all the people I know who have had cataract surgery they are also dealing with some kind of cancer hmmmm…..

Because it's the same think an autoimmune disease caused by infections:

Glaucoma is an autoimmune disease​

Abstract​

Glaucoma is characterized by retinal ganglion cell (RGC) neurodegeneration. Elevated intraocular pressure (IOP) is a major risk factor however, mechanisms independent of IOP play a role in RGC pathology. Both antibodies and CD4 T-cells as well as microbiota take part in the pathogenesis of both glaucoma and rheumatoid arteritis (RA).Heat shock proteins (HSPs) which originate in bacteria cross-react with RCG epitopes and were involved in rat model of retinal injury. Enhanced expression of HSPs in the retina was associated with glaucoma-like neuropathology and previous studies have also suggested a pathogenic role for HSPs in RA. In view of these data we suggest that glaucoma should be included in the spectrum of autoimmune diseases and that proven medications for RA should be adopted as an innovative IOP -independent therapeutic strategy for glaucoma.

Glaucoma is an autoimmune disease - PubMed

Glaucoma is characterized by retinal ganglion cell (RGC) neurodegeneration. Elevated intraocular pressure (IOP) is a major risk factor however, mechanisms independent of IOP play a role in RGC pathology. Both antibodies and CD4 T-cells as well as microbiota take part in the pathogenesis of both...

pubmed.ncbi.nlm.nih.gov

Obviously Rheumatoid Arthritis is linked to Glaucoma:

Rheumatoid Arthritis Linked to Development of Glaucoma​

Rheumatoid Arthritis Linked to Development of Glaucoma

Authors call for further investigation of pathophysiological pathways between rheumatoid arthritis and primary open-angle glaucoma.

www.hcplive.com

Now the question is: is the Rheumatoid Arthritis linked to cancer?

Here Are the Types of Cancer Linked to Rheumatoid Arthritis

Rheumatoid arthritis (RA) may put you at a slightly increased risk for certain types of cancers—and possibly at a lower risk for others.

www.health.com

 

[Rinse & rePeat]

Because it's the same think an autoimmune disease caused by infections:

Glaucoma is an autoimmune disease​

Abstract​

Glaucoma is characterized by retinal ganglion cell (RGC) neurodegeneration. Elevated intraocular pressure (IOP) is a major risk factor however, mechanisms independent of IOP play a role in RGC pathology. Both antibodies and CD4 T-cells as well as microbiota take part in the pathogenesis of both glaucoma and rheumatoid arteritis (RA).Heat shock proteins (HSPs) which originate in bacteria cross-react with RCG epitopes and were involved in rat model of retinal injury. Enhanced expression of HSPs in the retina was associated with glaucoma-like neuropathology and previous studies have also suggested a pathogenic role for HSPs in RA. In view of these data we suggest that glaucoma should be included in the spectrum of autoimmune diseases and that proven medications for RA should be adopted as an innovative IOP -independent therapeutic strategy for glaucoma.

Glaucoma is an autoimmune disease - PubMed

Glaucoma is characterized by retinal ganglion cell (RGC) neurodegeneration. Elevated intraocular pressure (IOP) is a major risk factor however, mechanisms independent of IOP play a role in RGC pathology. Both antibodies and CD4 T-cells as well as microbiota take part in the pathogenesis of both...

pubmed.ncbi.nlm.nih.gov

Obviously Rheumatoid Arthritis is linked to Glaucoma:

Rheumatoid Arthritis Linked to Development of Glaucoma​

Rheumatoid Arthritis Linked to Development of Glaucoma

Authors call for further investigation of pathophysiological pathways between rheumatoid arthritis and primary open-angle glaucoma.

www.hcplive.com

Now the question is: is the Rheumatoid Arthritis linked to cancer?

Here Are the Types of Cancer Linked to Rheumatoid Arthritis

Rheumatoid arthritis (RA) may put you at a slightly increased risk for certain types of cancers—and possibly at a lower risk for others.

www.health.com

I can’t say the same thing about the people I know having some sort of cancer having rheumatoid arthritis.