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Retinyl Acetate Causing Severe Bone Pain?

Discussion in 'A' started by cellboy, Aug 8, 2018.

  1. cellboy

    cellboy Member

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    As the title says i've been getting severe bone and joint pain from changing to retinyl acetate. I used to take palmitate and even in the 20.000iu range bone pain never happened. Acetate is different though. 5.000iu(which is recommended by peat) and i can barely walk. I've stopped taking it 3 weeks ago and the pain is still there. I dont know what to do or what to take to get it out of my body. please help guys :(
     
  2. jitsmonkey

    jitsmonkey Member

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    have you had your Vitamin D levels checked?

    with or without having had them checked
    some quality vit d dosed modestly and some sunshine should improve things in the short run
     
  3. OP
    cellboy

    cellboy Member

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    thanks for the reply man. yeah i've been taking some extra d on top of sun exposure since getting those problems but do you maybe know why palmitate didn't gave me those issues?
     
  4. Blossom

    Blossom Moderator

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    A must read from Ella
     
  5. OP
    cellboy

    cellboy Member

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    Wow! Many thanks Blossom :thumbup:
     
  6. Blossom

    Blossom Moderator

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    You're welcome. I trust Ella's opinion on vitamin A.
     
  7. Blossom

    Blossom Moderator

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    I'm also no longer consuming foods fortified with synthetic A and feel better for it.
     
  8. baccheion

    baccheion Member

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    Vitamin D is recommended when taking vitamin A; therefore, vitamin K2 and magnesium as well (10 IU D3 : 40 IU palmitate : 2 mcg+ MK-4; 10 IU D3 : 20 IU acetate : 2 mcg+ MK-4).

    Bone pain can be due to aromatase inhibition, low vitamin D, low magnesium, and/or low vitamin K. Vitamin A increases osteoclast activity (bone resorption) and is balanced by vitamin D + K's effect on osteoblasts/osteocalcin.
     
  9. nwo2012

    nwo2012 Member

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    Synthetic A will act much like Accutane. Joint pain is one of the common side effects. Franko will likely reach climax over this thread.
    As suggested, Vit D and exra calcium are in order.

    Oh yeah K2 and Mg too. All should be ballanced.
     
  10. Jewbermensch

    Jewbermensch Member

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    I actually just tried retinil for the first time, 3 drops of the acetate form on my shoulder. I immediately noticed a creakiness develop in my shoulder. Worrisome...
     
  11. Travis

    Travis Member

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    The retinyl acetate ester is considerably more active than the triglyceride ester due to a greater water solubility. Moreover: this acetate ester exists in a one-lipid form; the retinyl glyceride exists in unison with two fatty acids, common being two medium-chained saturated ones. Retinyl glycerides are the animal storage forms found in foods, are even before it can become active the ester bond must be cleaved from the tri-, soon to be di-, glyceride via enzymatic hydrolysis. Retinyl acetate is under no such constraints, and can rightly be assumed more readily converted into retinoic acid. This little guy could float straight to retinol oxidase and become retinoic acid before it's due time. Retinol toxicologists, osteoporosis epidemiologists, and poison-control center receptionists know this; retinol acetate is considered perhaps . . . tenfold more active. Comparative dosimetry can be found in retinol review articles and that IOM report that had justified, and then had set, the current RDA.
     
  12. Travis

    Travis Member

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    If that's true, I hope his keyboard is damaged in the process.
     
  13. nwo2012

    nwo2012 Member

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    OT but your nickname sounds offensive.
     
  14. nwo2012

    nwo2012 Member

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    Haha nice one.
     
  15. Jewbermensch

    Jewbermensch Member

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    I'm a Jew in pursuit of the Ubermensch
     
  16. nwo2012

    nwo2012 Member

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    I thought jews were born superior, in their deluded opinion of course. Fair enough, good nickname for you then.
     
  17. Jewbermensch

    Jewbermensch Member

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    Aha glad you're here to banter, thought you were gonna report me or something
     
  18. nwo2012

    nwo2012 Member

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    Not at all mate, freedom to chose what you want to say or do is paramount imo.
     
  19. Kray

    Kray Member

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    Can I ask any of you on this thread to respond to some simple questions from reading what Blossom shared?

    First, if one is incorporating as many good foods as possible into their diet a la Peat, is Vit A supplementation really necessary, absent acne and other symptoms listed as good indicators?

    Second, if one does supplement, what dosage? I see that Retinyl Acetate is out, retinol is in- can you suggest which form(s) best/brands, if ok to say?

    Many thanks-
     
  20. baccheion

    baccheion Member

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    40 IU palmitate : 10 IU D3 : 2 mcg+ MK-4, or the RDA (2000-3000 IU).
     
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