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Retinil - Liquid Vitamin A

Discussion in 'IdeaLabs' started by haidut, May 8, 2015.

  1. OP
    haidut

    haidut Member

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    Multiply by about 9/5, so this means about 19,000 IU palmitate. The acetate has higher retinol equivalency than palmitate so it means lower amount is needed. In other words, you need 19,000 IU of the palmitate to match the effects of 10,000 IU acetate.
     
  2. PhilParma

    PhilParma Member

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    How dumb would it be to use this as an eye drop? For chronic dry eyes.

    The palmitate version I mean. I'm not going to drop ethanol into my precious eye holes.
     
  3. Amazoniac

    Amazoniac Member

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    - Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome. - PubMed - NCBI
    - Dry eye in vitamin D deficiency: more than an incidental association. - PubMed - NCBI
    - Vitamin D Supplementation for Patients with Dry Eye Syndrome Refractory to Conventional Treatment
    Didn't read any of them, was aware due to a few mentions about the association. It probably goes back to balancing these vitamins.
     
  4. tomisonbottom

    tomisonbottom Member

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    @haidut So I tried increasing my retinil dosage for the first time the last few months and eventually got really REALLY dry skin. I tooking it topically on my face, and that was where my skin was dry.

    Orange palms seems to be the only indicator mention for too much A, and my palms are not orange, so I assume it's the ethanol in the retinil?

    I have dandruff and acne issues both before and after increasing the A, so I'm not clear on if I need more, or less, or just a different type of A.
     
  5. Oniyogini

    Oniyogini Member

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    @haidut we got the dmso version, my hubby has solar keratosis so we wanted to try retinil. He has one spot on the shoulder and because it constantly gets irritated by the seat belt, it bleeds on and off. He has used Tocovit, Progest E , Simply Progesterone, CO but none has completely healed it. The Retinil stings a bit on topical application on me and actually makes this spot on his shoulder bleed immediatey. Should we try the oil version? will it stain through to his work shirts?
    Thank you.
     
  6. bzmazu

    bzmazu Member

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    you might also give 2% iodine topically a try...repeat till spot disappears
     
  7. Amazoniac

    Amazoniac Member

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    Maybe niacinamide with a bit of aspirin and honey. Gelatin can be used to coat the region as well.
     
  8. OP
    haidut

    haidut Member

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    Vitamin A is known to cause dry skin in high doses. Google for "retinol dry skin".
     
  9. OP
    haidut

    haidut Member

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    We do not have a DMSO version of retinil. We have an ethanol version which uses SFA esters + ethanol as solvent. You can try the palmitate version if the ethanol one is irritating.
     
  10. superhuman

    superhuman Member

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    @haidut i was wondering what is the absorption rate for this in terms of orally vs topically ? I heard topically was much less absorbed
     
  11. Oniyogini

    Oniyogini Member

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    @haidut Apologies, it's the ethanol I meant....feels like a dab of ice on application...
    Hubby is trying the iodine per @bzmazu ....will try the palmitate in awhile.
    thank you for your responses.
     
  12. kayumochi

    kayumochi Member

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    The solar keratosis on my forearms are mostly gone from taking aspirin and niacinamide orally. There is nothing for the dermatologist to remove with liquid nitrogen anymore. Recently I began applying niacinamide topically as well but too early to what effects it may have.
     
  13. Oniyogini

    Oniyogini Member

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    He applied a mixture of aspirin and niacinamide for months but it didn't help much...do you think pure niacinamide might?
     
  14. Sheik

    Sheik Member

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    @haidut I have an old bottle of Retinil that started smelling weird a few months ago. Do you think it's still good to use? It's the ethanol version.

    ...it might be because I kept it next to my Energin but judging by the smell I'd guess not.
     
  15. OP
    haidut

    haidut Member

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    In the SFA ester it is probably at least 50%. The lower absorption from topical route is compensated for by the longer half life. Also, keep in mind that oral route also does not put 100% of the dose into your blood. Most of it stays in the liver. So, topical should not be underestimated just because it means lower absorption as percentage of the dose. It is what ends up in the blood that counts.
     
  16. OP
    haidut

    haidut Member

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    Vitamin A has a very peculiar smell. Not sure what your smells like but if you have the acetate version then I would only worry about smell if it starts smelling like vinegar as it would mean it is breaking down into retinol and acetate.
     
  17. HealthisWealth

    HealthisWealth Member

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    So this is the reason for the thorne new metered dispenser. At first i didnt like it but weeks of using im starting to get accustomed. Im taking it like an eyedrop. Fast application.
     
  18. Amazoniac

    Amazoniac Member

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    It's probably related to cost as well, so I guess it's a bi-winning case: we win here, they win there.
     
  19. HealthisWealth

    HealthisWealth Member

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    @Amazoniac

    and it really lessens the spillage. It will better if metered dispenser will be the standard on all k2, d3, A supplements..
     
  20. Amazoniac

    Amazoniac Member

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