goodandevil
Member
- Joined
- May 27, 2015
- Messages
- 978
PMID- 18042305
OWN - NLM
STAT- MEDLINE
DA - 20080423
DCOM- 20080623
LR - 20151119
IS - 1475-2662 (Electronic)
IS - 0007-1145 (Linking)
VI - 99
IP - 6
DP - 2008 Jun
TI - Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat
intakes: results from the European Prospective Investigation into Cancer and
Nutrition (EPIC)-Norfolk population study.
PG - 1335-43
AB - Evidence exists that a more acidic diet is detrimental to bone health. Although
more precise methods exist for measurement of acid-base balance, urine pH
reflects acid-base balance and is readily measurable but has not been related to
habitual dietary intake in general populations. The present study investigated
the relationship between urine pH and dietary acid-base load (potential renal
acid load; PRAL) and its contributory food groups (fruit and vegetables, meats,
cereal and dairy foods). There were 22,034 men and women aged 39-78 years living
in Norfolk (UK) with casual urine samples and dietary intakes from the European
Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk FFQ. A
sub-study (n 363) compared pH in casual samples and 24 h urine and intakes from a
7 d diary and the FFQ. A more alkaline diet (low PRAL), high fruit and vegetable
intake and lower consumption of meat was significantly associated with a more
alkaline urine pH before and after adjustment for age, BMI, physical activity and
smoking habit and also after excluding for urinary protein, glucose, ketones,
diagnosed high blood pressure and diuretic medication. In the sub-study the
strongest relationship was found between the 24 h urine and the 7 d diary. In
conclusion, a more alkaline diet, higher fruit and vegetable and lower meat
intake were related to more alkaline urine with a magnitude similar to
intervention studies. As urine pH relates to dietary acid-base load its use to
monitor change in consumption of fruit and vegetables, in individuals, warrants
further investigation.
FAU - Welch, Ailsa A
AU - Welch AA
AD - Department of Public Health and Primary Care, University of Cambridge,
Strangeways Site, Wort's Causeway, Cambridge CB1 8RN, UK.
[email protected]
FAU - Mulligan, Angela
AU - Mulligan A
FAU - Bingham, Sheila A
AU - Bingham SA
OWN - NLM
STAT- MEDLINE
DA - 20080423
DCOM- 20080623
LR - 20151119
IS - 1475-2662 (Electronic)
IS - 0007-1145 (Linking)
VI - 99
IP - 6
DP - 2008 Jun
TI - Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat
intakes: results from the European Prospective Investigation into Cancer and
Nutrition (EPIC)-Norfolk population study.
PG - 1335-43
AB - Evidence exists that a more acidic diet is detrimental to bone health. Although
more precise methods exist for measurement of acid-base balance, urine pH
reflects acid-base balance and is readily measurable but has not been related to
habitual dietary intake in general populations. The present study investigated
the relationship between urine pH and dietary acid-base load (potential renal
acid load; PRAL) and its contributory food groups (fruit and vegetables, meats,
cereal and dairy foods). There were 22,034 men and women aged 39-78 years living
in Norfolk (UK) with casual urine samples and dietary intakes from the European
Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk FFQ. A
sub-study (n 363) compared pH in casual samples and 24 h urine and intakes from a
7 d diary and the FFQ. A more alkaline diet (low PRAL), high fruit and vegetable
intake and lower consumption of meat was significantly associated with a more
alkaline urine pH before and after adjustment for age, BMI, physical activity and
smoking habit and also after excluding for urinary protein, glucose, ketones,
diagnosed high blood pressure and diuretic medication. In the sub-study the
strongest relationship was found between the 24 h urine and the 7 d diary. In
conclusion, a more alkaline diet, higher fruit and vegetable and lower meat
intake were related to more alkaline urine with a magnitude similar to
intervention studies. As urine pH relates to dietary acid-base load its use to
monitor change in consumption of fruit and vegetables, in individuals, warrants
further investigation.
FAU - Welch, Ailsa A
AU - Welch AA
AD - Department of Public Health and Primary Care, University of Cambridge,
Strangeways Site, Wort's Causeway, Cambridge CB1 8RN, UK.
[email protected]
FAU - Mulligan, Angela
AU - Mulligan A
FAU - Bingham, Sheila A
AU - Bingham SA