Regular Aspirin Intake Lowers Prostate And Colon Cancer Risks

haidut

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Another study among the countless that show aspirin can prevent cancer. Since this was presented during conference proceedings in Florence I can't find the study or info on doses. Maybe @Such_Saturation can help??
Five years of regular aspirin intake lowered prostate cancer risk by 60%+ and colon cancer by 30%+.
I think we are way overdue for aspirin to start trials on treating cancer. Enough on prevention.

Aspirin can protect against prostate cancer - WEST
"...Regular aspirin intake can decrease the risk of prostate cancer by almost 40%. A percentage that rises to 60% if this medicine is regularly taken for five years. Furthermore, in colorectal cancer the risk reduction amounts to 30%, according to a study conducted by the Italian Society of General Medicine (SIMG) on a sample of 13,453 patients suffering from cardio-vascular diseases. The results of the study were presented on the occasion of the 33rd National Congress of the Italian Society of General Medicine which was held in Florence."
 
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Seems a bit early for the proceedings x)
 

haidut

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Wilfrid

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@haidut,

Here is the link to the full study:
https://cyber.sci-hub.cc/MTAuMTAwMi9pamMuMzAwNjE=/lapi2016.pdf

And the abstract from PubMed:

Int J Cancer. 2016 Jul 1;139(1):205-11. doi: 10.1002/ijc.30061. Epub 2016 Mar 15.
Risk of prostate cancer in low-dose aspirin users: A retrospective cohort study.
Lapi F1, Levi M1,2, Simonetti M1, Cancian M3, Parretti D3, Cricelli I1, Sobrero A4, Cricelli C3.
Author information
  • 1Health Search, Italian College of General Practitioners and Primary Care, Florence, Italy.
  • 2Department of Health Sciences, University of Florence, Florence, Italy.
  • 3Italian College of General Practitioners and Primary Care, Florence, Italy.
  • 4Medical Oncology, IRCCS Ospedale San Martino IST, Genova, Italy.
Abstract
A growing body of evidence indicates that use of low-dose aspirin (LDA) reduces the risk of certain adenocarcinomas. While there are several and consistent findings on the protective effect of LDA on colorectal and other cancers, few and conflicting evidence is available on prostate cancer (PCa). The aim of this study was to assess whether LDA reduces the incidence rate of PCa. We conducted a nationwide, population-based, retrospective cohort study by using Health Search IMS Health Longitudinal Patient Database (HSD). Patients with ischemic cardio- or cerebrovascular disease (index date) were identified. Time-dependent multivariable Cox proportional hazard models were adopted to estimate Hazard Ratios (HRs) and related 95% confidence intervals (95% CI) of PCa associated with use of LDA. The exposure was lagged by one year to consider the latency of drug effect on the outcome onset. Within a cohort 13,453 patients, the overall incidence rate of PCa was 2.5 per 1,000 person-years. Use of LDA was associated with a decreased incidence rate of PCa (HR = 0.64; 95% CI: 0.48-0.86), which was primarily driven by a frequency of LDA use equal to or higher than twice per week (HR = 0.60; 95% CI: 0.43-0.83). Such an association was more pronounced (HR = 0.43; 95% CI: 0.21-0.91) when LDA was used for five or more years. Our findings indicate that LDA use might be associated with a reduction of risk of PCa in patients with cardio- or cerebrovascular diseases.

If the link to the full study do not work, just using the doi ref on sci-hub should do the trick.
 
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There are plenty of such studies. I'm interested as well in studies where they use aspirin to treat cancer. There are few such studies.
 

What-a-Riot

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@Amazoniac im still confused as to how much aspirin that is. Is 5 gr. 5 grains as in almost 2 grams? Is that what one aspirin tablet ever was?
 

haidut

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It's the amount mentioned by our bulgarian supercentenarian: 325mg.

And yet he's almost half Peat's age :): Now, if you count Peat-years to be like dog-years then sure.
 

haidut

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Speaking of which, this year (2016) Peat turned 80. Or maybe he is about to, but he said he was born in 1936 so in any event the big event is this year and we should send him a present.
 

haidut

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Do you realize that you don't actually post, but instead leave traces for your future biographer?

Lol, sounds like something you'd say about pboy ;)
 
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