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Ray Peat’s Methylene Blue Experience, And Optimal Dose Of Methylene Blue According To Ray Peat

Discussion in 'Methylene Blue' started by Logan-, Dec 23, 2018.

  1. Logan-

    Logan- Member

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    In John Barkhausen’s “Politics and Science podcast”, the topic was evolution. The recording is dated 2015.03.04.

    At around 1:18:00, someone asks Ray about his methylene blue experience. He says he takes Methylene Blue transdermally. He also says that “quite a few people are having very powerful anti-depressant effects from it with just one miligram a day. I think it is going to be effective at doses analogous to thyroid hormone – 20, 30, 40 micrograms I think might be the optiomal dose of Methylene Blue”.

    Just before that sentence, he says: “my approach to understanding new chemicals is to find what the smallest amount does and then work up in stages, and so far, I see it as a good anti-inflammatory.”

    So he uses MB transdermally, and uses very small doses.

    What do you think?
     
  2. Andman

    Andman Member

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    Thanks for the quotes, after a few unpleasant experiments i also keep the MB dosage very low
     
  3. methylenwhite

    methylenwhite Member

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    I've already asked in another MB tread about dilution of MB powder and got no answer. Will ask again here. I have MB powder and I need someone to verify my calculations.
    Every ml of water has 20 drops. I want 500 mcg of MB per drop. So it means I have to dilute 10.000 mcg in each ml. I have 30ml eye dropper flask. 300mg of MB powder per 30ml of water, right?
     
  4. Steven Bussinger

    Steven Bussinger Member

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    This doesn't answer your powder dilution request, however, it's good for posterity. Quoting from a review of the Kordon 2.3% product on Amazon:

     
  5. methylenwhite

    methylenwhite Member

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    Thanks. Ive made already two dilutions I believe they are 500mcg and 50mcg per drop. 50mcg once a day feels great, I can feel improvements and I crave more. Literally crave a couple of drops more.
     
  6. Ignatius

    Ignatius Member

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    I wonder could responding poorly to a 0.5 - 1mg dose of methylene blue be indicative of anything. Excess serotonin perhaps?
     
  7. Rick_F

    Rick_F Member

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    I think so. I've found small doses of Metergoline -a serotonin antagonist- will reduce the headaches I reliably get the next day from .5mg MB. I think this indicates serotonin is involved to some extent.
     
  8. postman

    postman Member

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    Yeah I remember it, he spoke about methylene blue on a radio show once and then people on forums and facebook groups started taking 100x the dose he suggested, getting the serotonin raising MAOI effect instead of the anti-inflammatory effect you want. And then the usual suspects started selling high dose methylene blue supplements.
     
  9. James b

    James b Member

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    Can you remember what KMUD radio show he spoke about it on, and can you recall what dosage he recommended? 0.5mg?
     
  10. ecstatichamster

    ecstatichamster Member

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    I wish I could remember. I listen to so many.
     
  11. jb116

    jb116 Member

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    Check out the "Nitric Oxide" "Current Trends On Nitric Oxide" and "You are what you Eat" episodes
     
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