PUFA Toxicity Mechanisms Breakdown

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Nov 11, 2014
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I've been through several papers and most of Peats material. I wanted to dedicate this thread to go through the logic of Peat-like theories of PUFA (or rather, all non-saturated fatty) action in the body in the short and long term. Let's be clear here, I'm not pro-PUFA at all; I'm just trying to be explicit to clarify mechanisms (which ones we think are the most significant, etc).

Mechanisms for PUFA-related degeneration in the body:
1) PUFAs are oxidized in certain situations (oxidation theory of aging)

2) PUFAs create inflammation via several mechanisms (list mechanisms:)
-- high omega 6 in cells
-- ???

3) decrease metabolism (list mechanisms:)
-- not sure if this is known

Can you all help me fill this out? I'd love for this to read like a textbook.
Thanks :)
 

tara

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