PUFA Effects Well Known In Australia

chispas

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Are they taking full credit? Nothing annoys me more. A famed GH researcher in bodybuilding circles regularly had the work published on his private forum plagiarized. Except he commanded enough respect across the bodybuilding culture that said plagiarism was usually called out and the plagiarizer heckled into obscurity.

I don't know, but are Peat's discoveries and ideas really something to be protected, or do they just reflect an alignment with an idealised metabolic state? It's like, engines need the correct oil to run, it shouldn't be a secret that takes decades to unravel. That's partly why indigenous populations pass their knowledge and customs down through the ages - because they know it works well in their environmental context. It's the spirit of "progress" that has ruined modern civilisation and required medicine to fix its symptoms.
 
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haidut

haidut

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Why do you take an article and use it as an example to corroborate a determined position, and picking just selected parts at your convenience and hidding others, instead of analizing it in context to expose it's whole idea?

Or didn't you see part 13. Why the Mediterranean diet worked?
Then one can understand the article sees not only just n-6 as bad, but the lack of a balanced ratio with the n-3 too.

That article you linked in its whole, matches more with my criteria and the studies posted about the significance of a balanced ratio on n6:n3 than what you echoes with.


As for the cholesterol ridiculous stigma there's no need to seek in remote journals or blogs; Uffe Ravnskov has been talking about this since 1991, and much before Peat btw.

I did see part #13. The problem is that the claim about omega-3 being the protective factor in the Mediterranean diet has been disproved. First of all, the fish in the Mediterranean have a lot less omega-3 than fish like salmon. Not even sure why the article mentions salmon in relation to the Mediterranean diet, this is not a commonly consumed fish in those regions. Also, the warmer the water the fish lives, the more saturated its fat. So, people in that region of the world consume a lot less omega-3 per capita than say Scandinavian countries. More importantly, the epidemiological trials with the Mediterranean diet that showed benefit for CVD inspired a few large randomized controlled trials with omega-3 for CVD and brain conditions. Those have mostly failed to show any benefit. So, even if there is a benefit for health in the actual Mediterranean diet it is probably not the omega-3.
http://www.medpagetoday.com/cardiology/prevention/38969
http://well.blogs.nytimes.com/2015/03/30/fish-oil-claims-not-supported-by-research/?_r=0
Omega-3 Supplements Don’t Lower Heart Disease Risk After All | TIME.com

Finally, simply biochemically EPA is highly unlikely to be beneficial as it is a precursor to prostaglandins and leukotrienes, both if which have been implicated in CVD (e.g. chronic low grade inflammation). Aspirin and leukotriene antagonists like montelukast, which both have solid evidence for preventing CVD, act largely in opposition to EPA and DHA.
Eicosapentaenoic acid - Wikipedia
"...Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega-3 fatty acid. In physiological literature, it is given the name 20:5(n-3). It also has the trivial name timnodonic acid. In chemical structure, EPA is a carboxylic acid with a 20-carbon chain and five cis double bonds; the first double bond is located at the third carbon from the omega end. EPA is a polyunsaturated fatty acid (PUFA) that acts as a precursor for prostaglandin-3 (which inhibits platelet aggregation), thromboxane-3, and leukotriene-5 eicosanoids. Studies of fish oil supplements, which contain EPA, have failed to support claims of preventing heart attacks or strokes.[1][2][3]"

Docosahexaenoic acid - Wikipedia
"...DHA is a major fatty acid in sperm, brain phospholipids and the retina. While the potential roles of DHA in the mechanisms of Alzheimer's disease are under active research,[10] studies of fish oil supplements, which contain DHA, have failed to support claims of preventing cardiovascular diseases.[11][12][13]."


Leukotriene antagonists (e.g. montelukast) and CVD prevention:
Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease. - PubMed - NCBI
Leukotriene modifiers as potential therapeutics for cardiovascular disease : Article : Nature Reviews Drug Discovery
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04338.x/pdf
http://www.medscape.org/viewarticle/563081
 

Agent207

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Also, the warmer the water the fish lives, the more saturated its fat. So, people in that region of the world consume a lot less omega-3 per capita than say Scandinavian countries. More importantly, the epidemiological trials with the Mediterranean diet that showed benefit for CVD inspired a few large randomized controlled trials with omega-3 for CVD and brain conditions. Those have mostly failed to show any benefit. So, even if there is a benefit for health in the actual Mediterranean diet it is probably not the omega-3.
Study: Omega 3 Fails to Prevent Heart Attacks
http://well.blogs.nytimes.com/2015/03/30/fish-oil-claims-not-supported-by-research/?_r=0
Omega-3 Supplements Don’t Lower Heart Disease Risk After All | TIME.com

Bear in mind the Mediterranean diet is NOT characterized by low pufa; not high, but definitely not ultra low. It's mayor fat contribution is mufa, mainly from olives; but also some omega3 from sardines, anchovies and walnuts its not uncommon.

I'm a bit of skeptical about trials using isolated omega3 supplements -these are very delicated substances that easily turn bad just by looking at them- compared to them being "naturally encapsulated" in their whole foods, and usually alongside with other protecting factors like vitamin e.

I'm not a big fan of fish oil, but specially if it comes from supplements.
 
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