Parsifal said:post 104500Could this cause apathia and/or anhedonia as well? How do this work? By lowering ACTH?haidut said:post 74456Peata said:Yesterday I took 500 mg. glycine and 1 g. taurine after a meal and it made me calm and drowsy. Not that I was unable to function, but I felt like curling up for a nap. This would be a good effect if taken before bed, but not during the day for me.
As both amino acids are GABA agonists I am not surprised at all. I personally take glycine/taurine only at night. Also, high doses can lead to depersonalization like other GABA agonists. Try 15g of taurine a day and you will see what I mean.
Apathy yes, anhedonia probably no. Anhedonia is a symptom of depression and high serotonin. And yes, GABA agonists downregulate ACTH and as such some of them are approved for Cushing disease.
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