Motorneuron
Member
- Joined
- Jan 29, 2021
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- 444
Progesterone upregulates TGF-b isoforms (b1, b2, and b3) expression in normal human osteoblast-like cells - PubMed
Transforming growth factors-beta (TGF-b1, -b2, and -b3) is secreted from osteoblasts and act as an anabolic factor through its influence of osteoblast proliferation and differentiation and on the synthesis of bone matrix. The ability of progestins to promote bone formation is attributed to their...
pubmed.ncbi.nlm.nih.gov
why should it be an antifibrotic?