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Progestene - Liquid Progesterone (bioidentical)

Discussion in 'IdeaLabs' started by haidut, Aug 6, 2015.

  1. Janelle525

    Janelle525 Member

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    Also potassium. I notice when I run out of bananas, progesterone will give me a pounding heart. It may increase sodium retention in some people.
     
  2. gp3690

    gp3690 Member

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    @haidut I suspect I have ankylosing spondilitis. My back/rib cage is extremely sore when I wake up in the morning for the past year or so. After reading Blocking Tissue Destruction by Ray Peat, I am thinking about supplementing with tyromix and possibly a small amount of progestene to combat this. I have taken tyromix in the past with results that I could not tangibly feel. Body temp hovers around 97.7-98.1 . I did not get a blood test after taking tyromix. I am hypothyroid (TSH of 4) and have hypogonadism ( steroid when I was 20). although I have not lost any sexual function in regards to libido, erection, ejaculation etc. I am a 27 YO male. Am I on a path you would recommend to someone in my situation re: progestene and tyromix
     
  3. OP
    haidut

    haidut Member

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    I think a combination of progesterone/DHEA or pregnenolone/DHEA would be better for hypogonadism than pure progesterone, and the first combination can probably improve thyroid function on its own (with no or very little added thyroid). Aspirin and magnesium have also been reported to help with that condition.
     
  4. gp3690

    gp3690 Member

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    In regards to the arthritis, would thyroid be of use? Would DHEA aggravate estrogen symptoms in someone who is hypothryroid? (gyno)
     
  5. cihans

    cihans Member

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    Hi @haidut pregnenolone/DHEA combination is the way I chose and I’m wondering if it must be cycled or not I’m in this combination via supplements for 1 month. Do you think continous use beneficial?
     
  6. OP
    haidut

    haidut Member

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    If you feel like the effects are staring to wane, it usually help to take a week off and then resume at the same dose.
     
  7. cihans

    cihans Member

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    Thank you for your reply.I feel Pregnenolone keeps me less bloated and mood is good. I checked my november blood work and my DHEA-S is 344.8 ug/dl ( ref: 102.6 - 416.3) it’s close to upper limit. Do you think that still need DHEA-S in the combination or only pregnenolone is enough?
     
  8. Joeyd

    Joeyd Member

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    am i right in thinking each bottle contains about 600mg progesterone

    wheras Progest-e contains around 2800mg per bottle.

    theyre a similar price, is there something different in the quality to explain such a massive difference in total progesterone content
     
  9. OP
    haidut

    haidut Member

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    Yes, your calculation is right. However, the absorption of our product should be much higher due to the SFA esters + ethanol solvent, so the effects would be the same as a much higher dose of proegsterone as in Progest-E. You can't compare any two products just based on contents. It is the effects that matter just as much.
     
  10. superhuman

    superhuman Member

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    Anyone notice different between using it topical vs oral ?
     
  11. johnwester130

    johnwester130 Member

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    why do people oral absorption is 100% through the gums though ?
     
  12. jb116

    jb116 Member

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    Through the gums is technically not oral, it is a type of topical route.
     
  13. aquaman

    aquaman Member

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    Yeah it’s madness to buy this over Progestene-e.

    It’s 4x more expensive, even if it’s supposedly “better absorbed”, which I don’t see how this could be proven??

    In the last podcast, Peat said the study for the TBI brain study could have used up to 1000mg a day with safety. Which is 1.5x what this single bottle supplies.
     
  14. Owen B

    Owen B Member

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    4-6 week report on Progestene, 15 mgs/day.

    Not great by itself. I got racing pulse, agitation. Adrenaline?

    My D3 tanked and my free T went below range.

    I'd love to get this into my system for its anti-cortisol effect in muscles (maybe in the skin, too, since there are a lot of GR receptors there, no?). But this needs to be balanced with something more androgenic.

    I looked at a TRT clinic and I didn't like what they were doing. It was $55 a week for a 110 mg. injection. Propionate?. I think it's a racket. Even if I had the $55 I don't think I would have done it.

    Maybe a urologist.

    If I take the Progestene again I'm going to cycle it. Maybe a week on, week off.
     
  15. jb116

    jb116 Member

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    Might be too much for you. Age?

    Also, males especially, may tend to not get enough calcium and sodium when increasing progesterone. Sodium especially since progest powerfully opposes aldosterone.
     
  16. OP
    haidut

    haidut Member

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    Why not try CortiNon or combine with androsterone?
     
  17. Wagner83

    Wagner83 Member

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    Isn't the dose quite high?
     
  18. OP
    haidut

    haidut Member

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    Well, 4 drops CortiNon would be 5mg progesterone and he seems to have been using 15mg progesterone for quite some time. So, it is less...unless I am missing something.
     
  19. Owen B

    Owen B Member

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    15-20 mgs. I think is the recommended dosage for the anti-cortisol effect.

    Androsterone gives me a strong thyroid feeling, then the reverse. Instead of heat, I get cold.

    I think I'll give DHEA another try, but I typically have not done well with it.

    I honestly don't know about my calcium, but I did pick up some D3 the other day.
     
  20. Owen B

    Owen B Member

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    Wait...am I missing something? Is the 15-20mg too much?

    For the DHEA, I thought, e.g., that 2-1, prog/DHEA was OK.
     
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