readforjoy
Member
- Joined
- Jul 5, 2013
- Messages
- 42
Does anyone take pregnenolone AND progesterone? Is it ok to do that?
Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Click Here if you want to upgrade your account
If you were able to post but cannot do so now, send an email to admin at raypeatforum dot com and include your username and we will fix that right up for you.
tomisonbottom said:Yes and Yes.
Pregnenolone will help you make more progesterone if you're short on it.
readforjoy said:My experience was that, no, pregnenolone did NOT do what I needed it to do. I needed progesterone, by preg made my estrogen dominant symptoms WAY worse. I was taking 100-120 mg pregnenolone per day. Now I am only on progesterone and doing much better.
readforjoy said:My experience was that, no, pregnenolone did NOT do what I needed it to do. I needed progesterone, by preg made my estrogen dominant symptoms WAY worse. I was taking 100-120 mg pregnenolone per day. Now I am only on progesterone and doing much better.
He also says that it's pretty harmless in high doses. But I don't see anywhere that he says taking 100mg or more a day is therapeutic. Maybe I missed that. Once you're taking as much as a healthy young person could ever make, more would seem likely to unbalance the system.Pregnenolone is largely converted into two other "youth-associated" protective hormones, progesterone and DHEA. At the age of 30, both men and women produce roughly 30 to 50 mg. of pregnenolone daily. When taken orally, even in the powdered form, it is absorbed fairly well. One dose of approximately 300 mg (the size of an aspirin tablet) keeps acting for about a week, as absorption continues along the intestine, and as it is "recycled" in the body. Part of this long lasting effect is because it improves the body's ability to produce its own pregnenolone. It tends to improve function of the thyroid and other glands, and this "normalizing" effect on the other glands helps to account for its wide range of beneficial effects.
himsahimsa said:But I don't see anywhere that he says taking 100mg or more a day is therapeutic. Maybe I missed that.
Ray Peat said:A tenth of a gram is a reasonable first dose, though some people seem to need as much as 1 gram per day.
himsahimsa said:Wow!! What effects did you get. You must have felt it, no?
mas said:I started off with pregnenolone approx. 30 mg daily periodically taking a few days off for the last 4 months. It has helped somewhat with my hyper adrenaline POTS tachycardia and the jittery wired feeling. But with less adrenaline, exhaustion hits me quite badly especially mid-afternoon with periods of feeling lightheaded faint and brain fog that come over me just as if a net had dropped on me with this. I was hoping that the pregnenolone would do more but I am still trying.
I am just waiting for my Progest-e and Nutripak. I do think my high estrogen needs the progesterone. It is going to be quite a learning experience. I am going to need all the help that I can get.
Megin
classicallady said:mas said:I started off with pregnenolone approx. 30 mg daily periodically taking a few days off for the last 4 months. It has helped somewhat with my hyper adrenaline POTS tachycardia and the jittery wired feeling. But with less adrenaline, exhaustion hits me quite badly especially mid-afternoon with periods of feeling lightheaded faint and brain fog that come over me just as if a net had dropped on me with this. I was hoping that the pregnenolone would do more but I am still trying.
I am just waiting for my Progest-e and Nutripak. I do think my high estrogen needs the progesterone. It is going to be quite a learning experience. I am going to need all the help that I can get.
Megin
I'm off the pregnenolone now. Think my gut feeling about preg. is very similar to other women's posts above. Just doing menopausal dosage of Progest-E. I'm in my late 50s, with no thyroid supplement. I would like someone who knows their thyroid stuff to tell me if there is any indication for taking thyroid even if your temps and pulse are good, for other reasons such as eczema and dry skin, brain fog, moodiness. Should I avoid thyroid if my temps and pulse are good (in 98.0> range and 76-80 pulse rate throughout day, basal temp 97.8-98.0)?
Are you taking the Progest-e for menopause by any chance? Have you been taking the Nutripak or just starting? Are temps/pulse the deciding factors?
readforjoy said:[highlight=#ffff40]I'm wondering which "estrogen dominant symptoms" were made worse or just not effected and what had readforjoy taking pregnenolone as a strategy to get at them?[/highlight]
I started taking pregnenolone following this protocol to boost my cortisol which would then work synergistically with T3.
http://anabolicminds.com/forum/attachme ... c16%20.att
Thyroid hormone on its own made me much worse due to low cortisol. I took the pregnenolone in 2-4 divided doses throughout the day, typically 50 mg in morning, 50 mg at noon, and 10 or 20 mg late afternoon. That's how fast my body used it up and I would need more to restore my energy. It worked good for a few months, but then I got depressed, had headaches, and my brainfog and fatigue got much worse. My doctor and I think that too much of it was converting to estrogen (he tested my estrogen and it was really high), so I am now taking Prometrium and am doing really good (Progest-e would only last 30 minutes in me. Doc said I was poorly absorbing it. I'm doing much better with Prometrium staying in my system).