Fetch said:post 103558 haidut if you're still following this thread. Do you know if there is any difference between oral or topical pregnenolone like there is for DHEA? I have seen you mention using both forms. I've only been using topical but oral would be very convenient.
Oral pregnenolone has higher chance of staying as pregnenolone, even if some it metabolizes into downstream hormones. Topical pregnenolone will metabolize almost completely before reaching the blood stream. So, topical pregnenolone will metabolize into whatever the local tissue needs, but most likely progesterone and some androgens.
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