PQQ (!)


Apr 15, 2020
Like the rest of the Quinones, K2 and Q10, PQQ seems very in-line with Peat's health philosophies.


PQQ’s chemical properties are novel, somewhat like combining the best attributes of the vitamins:

  • ascorbic acid
  • riboflavin
  • pyridoxine (vitamin B-6)
…into one molecule. Under appropriate conditions, PQQ is capable of catalyzing repeated oxidation and reduction reactions on a per molecule or molar basis hundred of times more efficiently than ascorbic acid and is capable of modifying amino acids to produce products, such as those that result from B-6 dependent enzymes. Moreover, PQQ is very stable to heat and harsh chemical environments. Pyrroloquinoline quinone is also water soluble. The potential number of catalytic cycles (number of repeated reactions) depends very much on chemical stability. PQQ does not easy self-oxidize or destruct, which is not the case for many bioactive quinone-containing compounds (e.g. the red wine and chocolate bioflavonoids) or so-called enediols, such as ascorbic acid). Although PQQ (both the oxidized and reduced forms) is not an effective antioxidant in aqueous-based environments. PQQ in lipid solvents or when amino acids are present in aqueous systems is a very powerful antioxidant and used as a “gold standard” in chemical-based assays. The facts surrounding pyrroloquinoline quinone cofactor biochemistry are unique, novel, and are fundamental to PQQ’s ability to perform unique and novel biological applications.

It has been mentioned a few times even in 2012 on this forum. Ray Peat does not seem to take an interest in it but the effects seem beneficial, and unlike CoQ-10 no self destructing/oxiding mechanism.
EMF Mitigation - Flush Niacin - Big 5 Minerals

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