Potassium Investigation

Tenglish

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Nov 18, 2015
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I ended up reading a bit of the Menstrual Cycle by Dalton and noticing her description of symptoms being caused by water retention and high blood pressure. I am also reading Ling - Life.... and know that potassium retention is part of the main method of lowering blood pressure. It seems like Potassium can be used to treat menstrual discomfort. This bring me to Peat's discussion on Potassium vs insulin. It seems based on this: https://www.researchgate.net/publication/12392473_Insulin_Understanding_its_action_in_health_and_disease, that insulin doesn't really need to let sugar into the cells, though it activates GLUT proteins to such ends, it simply acts through the liver and central nervous system. So that suggests that Insulin is not the evil it is being made to be. Strangely Potassium is also inversely correlated with Progesterone, so I'm still looking for the mechanism and why on this...should I view them as substitutes? NSAIDs retain potassium too. So all that said I'm looking for good papers on how or what interaction potassium has on insulin sensitivity and I've found this: The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity and this: https://www.ias.ac.in/article/fulltext/jbsc/044/01/0019. Anyone got anything better or related? I would like a more articulated model of how potassium increases the insulin sensitivity (I'm thinking maybe extending the conformation of GLUT4 proteins?) and also how it reduces blood pressure?: 1. lowers blood glucose in a few ways, 2. pushes salt and water out of cells into plasma increasing volume reducing the force required to move blood around? Please correct me on any of this...at a minimum potassium a la Ling seems critical to all of what we are all looking into.
 

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