This is one thing I ought to try. I should order a USP grade to test out the effects of oral intake. In a few days, I'll begin easing my way to sleeping on a CO2 bath. But since urea also has a CO2 component, I wonder how salutary the effect it has on the body. Still, given that urine already has urea, I have to ask what urea intake brings to the table that urine isn't.Dr. Peat says dosages as high as 120g per day are safe. There is no osmotic effect and the urea helps water in cells organize and structure better. Urea goes in and out of cells without osmotic effects.