Laurence
Member
- Joined
- Aug 9, 2016
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- 23
Possible Inhibitors of ACE2, the Receptor of 2019-nCoV
Andrographis sounds interesting although this is just a gene simulation study. If I'm reading that correctly they simulated a 21 fold reduction in ACE2 gene expression?
The 4 TCM showed significant ability to decrease ACE2 expression, especially Andrographis (FC=21.57), Urtica (FC=11.59), and Sambucus (5.99). Indeed, some studies reported potential effects of anti-pneumonia for active ingredients from Andrographis[18,19], Urtica[20], Sambucus[21], and Astragalus[22].
Andrographis sounds interesting although this is just a gene simulation study. If I'm reading that correctly they simulated a 21 fold reduction in ACE2 gene expression?