Possibility Of Low Dose Accutane Stunting Penile Growth During Puberty?

[Johno]

Hello,

how likely is it that accutane stunts penile growth in teenage boys? I know accutane reduces androgens and IGF-1 but studies have shown that this reduction is only mild. I actually had my T levels tested during accutane treatment and they were in the 90% percentile for my age.
I was told that the androgens, that are still available, are plenty to do the job. I was told that penile growth during puberty only needs a minimum of androgens to be triggered and that the penis will reach its genetic potential as long as the hormones are in the normal range. I asked many guys who took accutane during puberty (age 13-16) and they said that their dicks still grew bigger during/after treatment. Some guys even grew well above average.. I asked on /r/bigdickproblems if some of them took accutane and still grew bigger and some of them actually did. So I tend to think that accutane has close to no effect on pubertal development. (I know, anecdotal evidence,.. but still.)
One guy even PM'd me with this "I took accutane at 14/15 by the time I was 16 I was 7 1/2 and by the time I was 17 I was 81/2 And now 18 I am 9". My dose increased as I got older."..


I am making this whole thread because I myself took accutane at the age of 16 and a half (only 10 mg per day though) for roughly 6 months. During this time I experienced no side effects at all... After that I needed a second round of accutane at the age of 19/20. I took 40 mg per day for 5 months during this time but I am fairly sure that my penis was done growing at this point anyway. Haven't really grown since I started to take accutane at the age of 16,5 but guys are supposed to grow into their twenties thats why I'm worrying.
I am around 6.5-7 inches long when I press the ruler into my bone and 5 inches around. Pretty average but I constantly ask myself if I could have been bigger without accutane or not... I think if accutane really had any potential to disrupt puberty it would effect other aspects of puberty aswell (not just penile growth) but there are literally zero reports on stunted puberty in teenage boys and teenagers are the biggest group of patients. common sense tells me that this medication has been around for nearly 40 years and if it had any significant effect on puberty/penile growth, it would have been reported by now. Accutane is also used at much higher doses for neuroblastoma in young children...

To go a bit deeper into the matter: accutane has been shown to only affect 5AR-1 but not 5-AR2 and 5-AR2 is the isoenzyme that is highly expressed in the genitals so am I right to assume that the androgens in this area dont get affected? 5AR-2 deficiency has been shown to cause micropenis but 5AR-1 deficiency has no effect on **** growth at all.

r/bigdickproblems - Anyone here who took accutane as a teenager?
r/bigdickproblems - Did any of you take accutane during teenage years? Did it affect your penis growth?

 

[Dhair]

Hello,

how likely is it that accutane stunts penile growth in teenage boys? I know accutane reduces androgens and IGF-1 but studies have shown that this reduction is only mild. I actually had my T levels tested during accutane treatment and they were in the 90% percentile for my age.
I was told that the androgens, that are still available, are plenty to do the job. I was told that penile growth during puberty only needs a minimum of androgens to be triggered and that the penis will reach its genetic potential as long as the hormones are in the normal range. I asked many guys who took accutane during puberty (age 13-16) and they said that their dicks still grew bigger during/after treatment. Some guys even grew well above average.. I asked on /r/bigdickproblems if some of them took accutane and still grew bigger and some of them actually did. So I tend to think that accutane has close to no effect on pubertal development. (I know, anecdotal evidence,.. but still.)
One guy even PM'd me with this "I took accutane at 14/15 by the time I was 16 I was 7 1/2 and by the time I was 17 I was 81/2 And now 18 I am 9". My dose increased as I got older."..


I am making this whole thread because I myself took accutane at the age of 16 and a half (only 10 mg per day though) for roughly 6 months. During this time I experienced no side effects at all... After that I needed a second round of accutane at the age of 19/20. I took 40 mg per day for 5 months during this time but I am fairly sure that my penis was done growing at this point anyway. Haven't really grown since I started to take accutane at the age of 16,5 but guys are supposed to grow into their twenties thats why I'm worrying.
I am around 6.5-7 inches long when I press the ruler into my bone and 5 inches around. Pretty average but I constantly ask myself if I could have been bigger without accutane or not... I think if accutane really had any potential to disrupt puberty it would effect other aspects of puberty aswell (not just penile growth) but there are literally zero reports on stunted puberty in teenage boys and teenagers are the biggest group of patients. common sense tells me that this medication has been around for nearly 40 years and if it had any significant effect on puberty/penile growth, it would have been reported by now. Accutane is also used at much higher doses for neuroblastoma in young children...

To go a bit deeper into the matter: accutane has been shown to only affect 5AR-1 but not 5-AR2 and 5-AR2 is the isoenzyme that is highly expressed in the genitals so am I right to assume that the androgens in this area dont get affected? 5AR-2 deficiency has been shown to cause micropenis but 5AR-1 deficiency has no effect on **** growth at all.

r/bigdickproblems - Anyone here who took accutane as a teenager?
r/bigdickproblems - Did any of you take accutane during teenage years? Did it affect your penis growth?

Why are you personally concerned about this? You are going to drive yourself crazy thinking about this, and it has no bearing on your life or your perfectly adequate penis. Consider occupying your time elsewhere.

 

[Johno]

Why are you personally concerned about this? You are going to drive yourself crazy thinking about this, and it has no bearing on your life or your perfectly adequate penis. Consider occupying your time elsewhere.

I know I shouldnt be worried by this because there is nothing I can change now but whats your opinion? Does it have any effect in your opinion?

 

[Aaron]

This thread is lame. First of all, if your measurements are exactly what you claim, you are in the 95th percentile for size in terms of both length and volume, not "average." And I am blown away that you believe the guy who told you his penis grew to 9" at 18.

Let me put this into perspective. One of the top 3 biggest penises to EVER grace the porn industry is Lexington Steele and his has been verified to be no more than 9" bone-pressed. 9" is so rare that you would be more likely to find a woman with boobs the size of basketballs.

You need to at least be semi-realistic about size before you try to address this issue. (As a sidenote, so you don't assume I have a microdick, I've had the same 99.9th percentile stature and length since I was 17. It hasn't grown since.)

 

[Iceman2016]

It may have had an effect, or it may not have... In the end, it makes no difference as there is nothing you can do about it now.

I think one of the biggest issues facing younger people and their sexuality is that everyone is being exposed to unrealistic ideals of what is "normal" due to earlier and more frequent exposure to online pornography. Many of the people being cast are already exceptional and not "average". Furthermore, the porn industry utilizes fish eye lenses and other techniques to further accentuate and exaggerate things. This distorts what young people (male and female) think is normal. Also, since everyone is always self reporting being 8, 9, or 10 inches, things are further confounded. I once heard a very inexperienced 19 year old girl mention that 12" is "about average"... I just thought to myself, wtf?

Anyway, you'll worry much less about this type of thing once you have a career and loving wife/partner, even if you can't stop worrying about it now.

 

[ecstatichamster]

It may have had an effect, or it may not have... In the end, it makes no difference as there is nothing you can do about it now.

I think one of the biggest issues facing younger people and their sexuality is that everyone is being exposed to unrealistic ideals of what is "normal" due to earlier and more frequent exposure to online pornography. Many of the people being cast are already exceptional and not "average". Furthermore, the porn industry utilizes fish eye lenses and other techniques to further accentuate and exaggerate things. This distorts what young people (male and female) think is normal. Also, since everyone is always self reporting being 8, 9, or 10 inches, things are further confounded. I once heard a very inexperienced 19 year old girl mention that 12" is "about average"... I just thought to myself, wtf?

Anyway, you'll worry much less about this type of thing once you have a career and loving wife/partner, even if you can't stop worrying about it now.

Yes indeed.

 

[Johno]

This thread is lame. First of all, if your measurements are exactly what you claim, you are in the 95th percentile for size in terms of both length and volume, not "average." And I am blown away that you believe the guy who told you his penis grew to 9" at 18.

Let me put this into perspective. One of the top 3 biggest penises to EVER grace the porn industry is Lexington Steele and his has been verified to be no more than 9" bone-pressed. 9" is so rare that you would be more likely to find a woman with boobs the size of basketballs.

You need to at least be semi-realistic about size before you try to address this issue. (As a sidenote, so you don't assume I have a microdick, I've had the same 99.9th percentile stature and length since I was 17. It hasn't grown since.)

Yeah I actually tend to think that I was done growing naturally at that age because I've seen many people stop growing between 16-17...

 

[SOMO]

Hello,

how likely is it that accutane stunts penile growth in teenage boys? I know accutane reduces androgens and IGF-1 but studies have shown that this reduction is only mild. I actually had my T levels tested during accutane treatment and they were in the 90% percentile for my age.
I was told that the androgens, that are still available, are plenty to do the job. I was told that penile growth during puberty only needs a minimum of androgens to be triggered and that the penis will reach its genetic potential as long as the hormones are in the normal range. I asked many guys who took accutane during puberty (age 13-16) and they said that their dicks still grew bigger during/after treatment. Some guys even grew well above average.. I asked on /r/bigdickproblems if some of them took accutane and still grew bigger and some of them actually did. So I tend to think that accutane has close to no effect on pubertal development. (I know, anecdotal evidence,.. but still.)
One guy even PM'd me with this "I took accutane at 14/15 by the time I was 16 I was 7 1/2 and by the time I was 17 I was 81/2 And now 18 I am 9". My dose increased as I got older."..


I am making this whole thread because I myself took accutane at the age of 16 and a half (only 10 mg per day though) for roughly 6 months. During this time I experienced no side effects at all... After that I needed a second round of accutane at the age of 19/20. I took 40 mg per day for 5 months during this time but I am fairly sure that my penis was done growing at this point anyway. Haven't really grown since I started to take accutane at the age of 16,5 but guys are supposed to grow into their twenties thats why I'm worrying.
I am around 6.5-7 inches long when I press the ruler into my bone and 5 inches around. Pretty average but I constantly ask myself if I could have been bigger without accutane or not... I think if accutane really had any potential to disrupt puberty it would effect other aspects of puberty aswell (not just penile growth) but there are literally zero reports on stunted puberty in teenage boys and teenagers are the biggest group of patients. common sense tells me that this medication has been around for nearly 40 years and if it had any significant effect on puberty/penile growth, it would have been reported by now. Accutane is also used at much higher doses for neuroblastoma in young children...

To go a bit deeper into the matter: accutane has been shown to only affect 5AR-1 but not 5-AR2 and 5-AR2 is the isoenzyme that is highly expressed in the genitals so am I right to assume that the androgens in this area dont get affected? 5AR-2 deficiency has been shown to cause micropenis but 5AR-1 deficiency has no effect on **** growth at all.

r/bigdickproblems - Anyone here who took accutane as a teenager?
r/bigdickproblems - Did any of you take accutane during teenage years? Did it affect your penis growth?

Since nobody else really answered your question:

1. Accutane affects SEBUM Glands/oil glands in the skin - you have a large concentration of these sebum glands in your GENITAL REGION.
Sebum is not just inert skin oils, sebum also interacts with hormone receptors.
The animal equivalent of sebum in sheep is Lanolin and it protects against external toxins and waterproofs the sheep's body. Accutane interferes with sebum production, often stopping it or reducing it drastically.

2. Accutane functions like a synthetic Vitamin A in the body and one of the things Vitamin A (retinol) is responsible for is preventing hyperkeratinization (basically callouses or keloid scar tissue, generally keratinization is related to skin on the surface, but Vit A plays a role in the skin shedding.)
By causing the skin to shed excessively, over time it can damage the skin and it's likely skin "growth" could be halted by scar tissue formation or hyperkeratinization.

3. As we know, skin everywhere stretches and grows during puberty and Accutane could definitely interfere in that process. I also would not expect long-term effects of accutane on pubertal growth to be a very profitable area of research and the truth is that medical research is generally done in the direction of identifying drug substances to turn into profit. In other words, by taking accutane you may have been an unwilling guinea pig.

Accutane is ineffective in maybe 10% of people, even though the vast majority for whom it works never struggle with skin issues again which is a huge plus and a good reason to take Accutane. I totally understand why someone with Acne or skin issues would want to take accutane, clear skin is valued in our society and people will judge you if your skin looks like crap. Accutane is overall quite safe and has a proven track record of success, however it's possible you may be one of those that react negatively to the drug. You know your body best, and if you feel like Accutane has affected you negatively, it probably has.

 

[Johno]

Since nobody else really answered your question:

1. Accutane affects SEBUM Glands/oil glands in the skin - you have a large concentration of these sebum glands in your GENITAL REGION.
Sebum is not just inert skin oils, sebum also interacts with hormone receptors.
The animal equivalent of sebum in sheep is Lanolin and it protects against external toxins and waterproofs the sheep's body. Accutane interferes with sebum production, often stopping it or reducing it drastically.

2. Accutane functions like a synthetic Vitamin A in the body and one of the things Vitamin A (retinol) is responsible for is preventing hyperkeratinization (basically callouses or keloid scar tissue, generally keratinization is related to skin on the surface, but Vit A plays a role in the skin shedding.)
By causing the skin to shed excessively, over time it can damage the skin and it's likely skin "growth" could be halted by scar tissue formation or hyperkeratinization.

3. As we know, skin everywhere stretches and grows during puberty and Accutane could definitely interfere in that process. I also would not expect long-term effects of accutane on pubertal growth to be a very profitable area of research and the truth is that medical research is generally done in the direction of identifying drug substances to turn into profit. In other words, by taking accutane you may have been an unwilling guinea pig.

Accutane is ineffective in maybe 10% of people, even though the vast majority for whom it works never struggle with skin issues again which is a huge plus and a good reason to take Accutane. I totally understand why someone with Acne or skin issues would want to take accutane, clear skin is valued in our society and people will judge you if your skin looks like crap. Accutane is overall quite safe and has a proven track record of success, however it's possible you may be one of those that react negatively to the drug. You know your body best, and if you feel like Accutane has affected you negatively, it probably has.

So in your opinion, its totally possible that accutane stunts **** growth? How did all these guys in the subreddit (links in original post) still grow bigger then? I dont know if accutane affected me negatively. I just know for sure that I took accutane at age 16 1/2 and didnt grow bigger after that anymore. I could have been done growing naturally, or it was accutane. and I want to find out how likely it is that accutane stunts penis growth or growth of the body in general