Penis Size Reduced From Finasteride

Drareg

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This is an interesting study and is being will,be used in lawsuits against finasteride if not now but soon,it will add weight to an overall argument.
The corpus cavernosum is hugely important to penis size,any reduction in this will actually reduce penis size guaranteed.(the corpora cavernosa which contain most of the blood in the penis during an erection)

This study on rats highlights a profound reduction in the size of penis after oral finasteride.


RESULTS:
Serum T and DHT and intraprostatic DHT concentrations, erectile function, and mean weights of the corpus cavernosum and prostate were lowest in group 2. There was no significant difference in the serum T concentration and erectile function between groups 4 and 1. However, the serum and intraprostatic DHT concentrations were significantly lower in group 4 than in group 1 (both P < 0.001). The tissue weights of the corpus cavernosum and prostate were reduced by 25.9% and 92.3% in group 4 compared with group 1 (both P < 0.001). Histopathology revealed a significant atrophy of the prostate in groups 2 and 4. There was a significant decrease in the smooth muscle content in group 2, but not in groups 3 and 4.

CONCLUSIONS:
In a rat model, finasteride treatment for 4 weeks reduces the weight of the corpus cavernosum but appears not to affect the erectile responses to electrical stimulation of the cavernous nerve. As erection is a complex process involving important signaling in the brain, further studies are necessary to demonstrate the long-term effects of finasteride on both central and peripheral neural pathways of erection.


Effects of oral finasteride on erectile function in a rat model. - PubMed - NCBI
 

RedStaR

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This is a rather old study and has been beaten to death on many forums before.

Besides, rat studies on finasteride are not quite comparable to human usage, or an argument can be made.
 

paymanz

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No doubt about it, penis size is not static, hormonal status affects it.

Especially erection quality is determinative factor. Hormones affects mostly erection quality in my personal experience.
 

TubZy

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Of course there is a chance there could be less blood flow while you take finasteride. Lower DHT means less blood flow to your penis, less blood flow smaller erections, given DHT regulates the release, but you wouldn't understand that you just want to eat dried bull testicles to get your wee wee to grow like the thread you created.

Body Builders And Dried Testicle Supplement

But nice try though, strawman rat study crew checking in.
 
Last edited:

RedStaR

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Of course there is a chance there could be less blood flow while you take finasteride. Lower DHT means less blood flow to your penis, less blood flow smaller erections, given DHT regulates the release, but you wouldn't understand that you just want to eat dried bull testicles to get your wee wee to grow like the thread you created.

Body Builders And Dried Testicle Supplement

But nice try though, strawman rat study crew checking in.

In the context of the study, it measured CC weight, not intracorporal pressure.
 

Wagner83

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Anything that reduces or destroys night tumescence will shrink size and possibly lead to fibrosis in the long run.
 

RedStaR

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Anything that reduces or destroys night tumescence will shrink size and possibly lead to fibrosis in the long run.

You don't need a lot of tumescences in the day to maintain tissue, something in the order of 15-30 minutes per day of semi-flaccidity was enough to avoid hypoxia-induced apoptosis.

On the other hand, I can recall finasteride and dutasteride reducing electrically stimulated erections and nocturnal tumescence.
 
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You don't need a lot of tumescences in the day to maintain tissue, something in the order of 15-30 minutes per day of semi-flaccidity was enough to avoid hypoxia-induced apoptosis.

On the other hand, I can recall finasteride and dutasteride reducing electrically stimulated erections and nocturnal tumescence.
Do you have a cite Thanks
 

Makrosky

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Anything that reduces or destroys night tumescence will shrink size and possibly lead to fibrosis in the long run.
I think this is a bit exagerated. In the nofap forums it's accepted that you will have a flat line where your penis will be flacid for days or weeks and after that erections come much more stronger than ever. Heaps of people have reported this.
 

Wagner83

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I think this is a bit exagerated. In the nofap forums it's accepted that you will have a flat line where your penis will be flacid for days or weeks and after that erections come much more stronger than ever. Heaps of people have reported this.
I'm talking about the erections you get during the night, not the day. You don't see them .
 

RedStaR

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I think this is a bit exagerated. In the nofap forums it's accepted that you will have a flat line where your penis will be flacid for days or weeks and after that erections come much more stronger than ever. Heaps of people have reported this.

Hypoxia-induced apoptosis or fibrosis is very real. PDE-5 inhibitors have shown time and time again to mitigate some of these effects in ED or androgen-deprived men to a large extent.
 
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Hypoxia-induced apoptosis or fibrosis is very real. PDE-5 inhibitors have shown time and time again to mitigate some of these effects in ED or androgen-deprived men to a large extent.

Disagree. In the longer run they make it worse by increasing VEGF. They are a disaster.
 

RedStaR

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Plenty of studies that show success over the long-run from chronic dosing in preventing fibrosis and maintaining fibrotic indicies from deteriorating. And some show imrpovements in androgen deprived enviroments or diabetes/prostatectomy induced ED.

Testosterone administration also promotes VEGF in the penis and reduces venous leakage.
 

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