ecstatichamster
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- Nov 21, 2015
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Fantastic study
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Tumors contain oxygenated and hypoxic regions, so the tumor cell population is heterogeneous. Hypoxic tumor cells primarily use glucose for glycolytic energy production and release lactic acid, creating a lactate gradient that mirrors the oxygen gradient ...
www.ncbi.nlm.nih.gov