PDE Inhibitor Enhances Verbal Working Memory

Xref

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Apr 9, 2020
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PDE Inhibitors are well known to exert specific effects on various tissues depending on subtype...
Specific PDE4 inhibitors elevate cAMP in selective brain areas associated with memory
Furthermore, the more specific we get we can see very selective enhancement

Caffeine is known to elevate cAMP but lacks selectivity and potency.

This study confirms the idea that specific and somewhat coherent elevation of cAMP leads to cognitive enhancement


Acute Administration of Roflumilast Enhances Immediate Recall of Verbal Word Memory in Healthy Young Adults
Acute Administration of Roflumilast Enhances Immediate Recall of Verbal Word Memory in Healthy Young Adults - PubMed
 

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