Pansterone - Liquid Pregnenolone/DHEA Mix

Lightbringer

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[ref]haidut[/ref], just wanted to confirm a couple of things:
a) Unlike estroban, this pansterone flows freely , so when I invert the bottle to apply some on my wrist, quite a bit comes out of the bottle and I can't really seem to get drops out. Is there something simple I'm missing?
b) Is this supposed to have a smell? almost a garlic-y smell on my wrists after application.
thanks
 

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Kaspar_Hauser said:
post 105657 [ref]haidut[/ref], just wanted to confirm a couple of things:
a) Unlike estroban, this pansterone flows freely , so when I invert the bottle to apply some on my wrist, quite a bit comes out of the bottle and I can't really seem to get drops out. Is there something simple I'm missing?
b) Is this supposed to have a smell? almost a garlic-y smell on my wrists after application.
thanks

Just use a paper clip
 
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Lightbringer

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Kaspar_Hauser said:
post 105657 [ref]haidut[/ref], just wanted to confirm a couple of things:
a) Unlike estroban, this pansterone flows freely , so when I invert the bottle to apply some on my wrist, quite a bit comes out of the bottle and I can't really seem to get drops out. Is there something simple I'm missing?
b) Is this supposed to have a smell? almost a garlic-y smell on my wrists after application.
thanks
Ignore (a) - I just poured it into a different bottle with a dropper so I can measure it as needed. Just wanted to confirm if the funky smell is expected and nothing to worry about? The smell does fade away after a while but initially its pretty strong.
 
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tara

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Garlicky smell confirms DMSO content. :)
 
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haidut said:
post 105950 Hi all,

I just wanted to let every body know that we have added tocopherol and organic olive oi to the supplement. There are many reasons but the two main ones are to mitigate the skin irritation that some people get from DMSO, and to reduce the smell. The doses of pregnenolone and DHEA are still the same and only the solvent has been changed with the hope to make it better. The supplement will now have a lot more tocopherol and olive oil and a lot less DMSO, but the DMSO is still enough to guarantee 100% absorption and enhancement of steroid activity.
I did not have problems with smell or skin irritation. :(

I wouldn't sell my last bottle of original Pansterone for a million dollars. :lol:
 
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Charlie said:
post 105983
haidut said:
post 105950 Hi all,

I just wanted to let every body know that we have added tocopherol and organic olive oi to the supplement. There are many reasons but the two main ones are to mitigate the skin irritation that some people get from DMSO, and to reduce the smell. The doses of pregnenolone and DHEA are still the same and only the solvent has been changed with the hope to make it better. The supplement will now have a lot more tocopherol and olive oil and a lot less DMSO, but the DMSO is still enough to guarantee 100% absorption and enhancement of steroid activity.
I did not have problems with smell or skin irritation. :(

I wouldn't sell my last bottle of original Pansterone for a million dollars. :lol:

OK, noted. Maybe we'll keep the door open. When somebody orders Pansterone they tell us if they want the original DMSO version. If they don't say anything they get the tocopherol + DMSO mix. So, no worries Charlie, we got you covered:):
 
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charlie

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haidut said:
post 105990 So, no worries Charlie, we got you covered:):
Gonna feel silly if I end up liking the other one better. :lol: :D

I think giving the option like you said would be optimal though. Hope its not too much trouble.

Thank you! :hattip
 
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haidut

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Charlie said:
post 105991
haidut said:
post 105990 So, no worries Charlie, we got you covered:):
Gonna feel silly if I end up liking the other one better. :lol: :D

I think giving the option like you said would be optimal though. Hope its not too much trouble.

Thank you! :hattip

Lol, whatever works better right? Yes, it's not a problem to keep both options and with time I'll be able to tell which option people prefer. The DMSO/ethanol has its advatnages like no greasiness and much faster absorption and dryout of the skin. No color either, which would be a problem with a tocopherol based supplement.
 
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Fetch

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Hi Haidut I just received my order of pansterone with the new formulation. According to the bottle there is no DMSO in this correct? I have only used one dose but for now I think I'm with charlie on this in that I like the DMSO. Maybe the oil preparation will be good for alternative application sites I'll just have to see. I understand why you made the change but if available in the future will be ordering the DMSO variety.
 
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Fetch said:
post 107361 Hi Haidut I just received my order of pansterone with the new formulation. According to the bottle there is no DMSO in this correct? I have only used one dose but for now I think I'm with charlie on this in that I like the DMSO. Maybe the oil preparation will be good for alternative application sites I'll just have to see. I understand why you made the change but if available in the future will be ordering the DMSO variety.

Thanks for the feedback. We have been receiving feedback from other people as well and as of now the number of people liking the DMSO outnumbers the ones disliking it in a ratio of 100:1. So, going forward we'll be using the DMSO formula. Sorry for the (brief) detour.
 
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Lightbringer

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haidut said:
post 93716
Zachs said:
I'm confused as to why the preg dose is only 5mg? Weren't you talking about 100g preg supplement in the other thread?

When pregenolone is taken on its own 100mg is probably OK. However, in combination with DHEA its conversion into all pathways is inhibited except the progesterone -> aldosterone pathway. So taking 100mg pregnenolone with DHEA may end up raising aldosterone and this blood pressure, which is something you don't want. So, pregnenolone and DHEA combination is quite different in effects from taking pregnenolone alone.
Also, we did some tests with volunteer and for virtually all of them anything more than 10mg of pregnenolone combined with 5mg DHEA made them feel jittery. The 1:1 gave everybody a feeling of calmness and energy, plus it made the males get pumped up muscles and women shiny skin:):
I was hoping to take advantage of a sale to order some pregnenolone but I remembered this comment. Would taking 100mg after about a couple of hours of taking Pansterone be ok ?
 
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Kaspar_Hauser said:
post 107367
haidut said:
post 93716
Zachs said:
I'm confused as to why the preg dose is only 5mg? Weren't you talking about 100g preg supplement in the other thread?

When pregenolone is taken on its own 100mg is probably OK. However, in combination with DHEA its conversion into all pathways is inhibited except the progesterone -> aldosterone pathway. So taking 100mg pregnenolone with DHEA may end up raising aldosterone and this blood pressure, which is something you don't want. So, pregnenolone and DHEA combination is quite different in effects from taking pregnenolone alone.
Also, we did some tests with volunteer and for virtually all of them anything more than 10mg of pregnenolone combined with 5mg DHEA made them feel jittery. The 1:1 gave everybody a feeling of calmness and energy, plus it made the males get pumped up muscles and women shiny skin:):
I was hoping to take advantage of a sale to order some pregnenolone but I remembered this comment. Would taking 100mg after about a couple of hours of taking Pansterone be ok ?

I would advise against it, but you can try. In my experience, probably due to the effects of pregnenolone potentiating the effects of DHEA, taking a hefty dose of additional pregnenolone on top of Pansterone seems too stimulating for most people.
 
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Kessry

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Hey Haidut,

I have suffered from chronic elevated cortisol (multiple blood tests, 24hour urine tests, and saliva tests to confirm it over the past 3 years) and low testosterone. Symptoms have been low libido (if not no sex drive at all), problems sleeping past 7am, frequent urination (unable to hold a glass of water in my body for longer than an hour it seems), cold feet and hands, dry skin, low energy, and in general a gloomy disposition. I may suffer from PFS, all of the "specialists" and Dr.'s I've seen over the past few years have been unable to come to any conclusion regarding that.

I have been taking Pansterone (8 drops, 2x a day) for about 2 weeks now and have noticed some great improvements:
-I am suddenly able to sleep in like I could as a teen
-I am no longer sensitive to the cold or find myself cold in places that people complain of being too warm
-Libido seems to be coming back (although I am cautiously optimistic on this one at this point)
-I seem to sweat more and my sweat has that classic male body odor smell again
-In general my mood has improved, I see opportunities instead of barriers in life and have been seeking social interaction more often
-Energy levels are definitely improved and more stable

Do you think the changes in the amount I am sweating and the smell of the sweat could be attributed to Pansterone? Also, about 3 days ago my weight jumped about 4lbs over night and has remained there ever since. I weigh myself every morning and have been stable for years, so this 4lbs. sustained jump is odd considering I've been eating the same (if not less) calories lately. Could this be water weight and do you think it is anything to be concerned about?
 
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Kessry said:
post 107520 Hey Haidut,

I have suffered from chronic elevated cortisol (multiple blood tests, 24hour urine tests, and saliva tests to confirm it over the past 3 years) and low testosterone. Symptoms have been low libido (if not no sex drive at all), problems sleeping past 7am, frequent urination (unable to hold a glass of water in my body for longer than an hour it seems), cold feet and hands, dry skin, low energy, and in general a gloomy disposition. I may suffer from PFS, all of the "specialists" and Dr.'s I've seen over the past few years have been unable to come to any conclusion regarding that.

I have been taking Pansterone (8 drops, 2x a day) for about 2 weeks now and have noticed some great improvements:
-I am suddenly able to sleep in like I could as a teen
-I am no longer sensitive to the cold or find myself cold in places that people complain of being too warm
-Libido seems to be coming back (although I am cautiously optimistic on this one at this point)
-I seem to sweat more and my sweat has that classic male body odor smell again
-In general my mood has improved, I see opportunities instead of barriers in life and have been seeking social interaction more often
-Energy levels are definitely improved and more stable

Do you think the changes in the amount I am sweating and the smell of the sweat could be attributed to Pansterone? Also, about 3 days ago my weight jumped about 4lbs over night and has remained there ever since. I weigh myself every morning and have been stable for years, so this 4lbs. sustained jump is odd considering I've been eating the same (if not less) calories lately. Could this be water weight and do you think it is anything to be concerned about?

Excellent, thanks for the feedback!
I notice the male odor sweat from Pansterone as well. Probably due to the conversion of DHEA into androsterone, which is a male pheromone. DHT tends to make sweat smell that way as well.
The extra weight could be from water retention, but it can also be from increased protein synthesis. Are you sure it happened overnight?
 
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Vinero

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I have received the pansterone dissolved in tocopherol and olive oil. Is absorption close to 100% do you think? Ray has said that in the case of progest-E that only about 10% of the progesterone gets absorbed if you take it topically. Since pansterone has the same solvents as progest-e, do you think that maybe the suggested 8 drops per dose is not enough and should be way higher?
 

Kessry

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haidut said:
post 107538

Excellent, thanks for the feedback!
I notice the male odor sweat from Pansterone as well. Probably due to the conversion of DHEA into androsterone, which is a male pheromone. DHT tends to make sweat smell that way as well.
The extra weight could be from water retention, but it can also be from increased protein synthesis. Are you sure it happened overnight?

Good to know that the odor change is expected, I prefer having my sweat smell manly again to be honest!

My thoughts exactly on the weight gain. It happened between one morning weigh-in and the next morning and has been consistently at this +4lbs. level since. Can an increase in DHT/DHEA cause water retention? If so, through which mechanisms? I would just like to understand it all better, I'm slightly worried that water retention could imply increased Estrogen.
 
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