Pansterone - Liquid Pregnenolone/DHEA Mix

[raypeatclips]

I have some reports from people using Calcirol and EstroBan so I will ask them to post their feedback/results in the respective threads.

Thank you that would be great.

 

[Jsaute21]

It has been three weeks since taking this again. Rat started back with 2 drops for one week and rat felt very sexual. The two weeks after 4 drops before bed.

Most noticeable the effect of decreased Free Fatty Acid liberation due to no foamy urine no matter if it is direct in the water.

Which solvent?

 

[japanesedude]

I found something 'white' stacked in under my toco/mct Pansterone's bottle.
tried to shake it but it didnt worked. Is it ok to use it just as usual?

 

[superhuman]

Anyone notice different between using it topical vs oral ?

 

[Wagner83]

Yes people have noticed a difference and so has Ray ("effects on the brain").

 

[superhuman]

Yes people have noticed a difference and so has Ray ("effects on the brain").

Ok. so ? using it topical or oral?

 

[Wagner83]

Ok. so ? using it topical or oral?

Ray takes it orally for the effects on the brain, while being vey cautious as very small amounts can enlarge the liver. If there's a local issue he wants to address he may use it on the skin. @haidut usually uses it topically (correct me if I'm wrong), the effects are more androgenic (helps muscle recovery too) as a few studies have shown elevated markers of androgenicity from topical dhea. Then people have reported different effects, estrogenic effects from topical and same orally, at least one or two members use one drop orally with good results, so I guess if you have it and want to use it, try both and decide. DHEA is tricky.

 

[superhuman]

Ray takes it orally for the effects on the brain, while being vey cautious as very small amounts can enlarge the liver. If there's a local issue he wants to address he may use it on the skin. @haidut usually uses it topically (correct me if I'm wrong), the effects are more androgenic and bigger doses can be used (helps muscle recovery too) as a few studies have shown elevated markers of androgenicity from topical dhea. Then people have reported different effects, estrogenic effects from topical and same orally, at least one or two members use one drop orally with good results, so I guess if you have it and want to use it, try both and decide.

Interesting. I have it yes, and have tried both approaches but i dont notice anything from either

 

[Wagner83]

Interesting. I have it yes, and have tried both approaches but i dont notice anything from either

Which solvent do you have and what dose did you try? Perhaps it could be a good sign, that you don't need it.

 

[superhuman]

Which solvent do you have and what dose did you try? Perhaps it could be a good sign, that you don't need it.

i have the sfa + ethanol. 4 drops aka 5 mg

 

[bobbity]

I have tried both SFA and MCT/Toco formulations of this product and find the latter to be far more effective. Anyone else noticed this?

 

[SB4]

To preface this I have quite bad CFS/POTS. I have experimented with lowish dose DHEA + PREG with good and bad effects. I have below reference range morning cortisol (1.74nmol/L [2.69-9.30]) and lowish DHEA.

I was taking too high a dose before so bought pansterone to try low dose. I am taking 1 drop in the morning every 5/6 days (still experimenting). I find oral to work better than topical.

Anyway I think that at even 1mg every 6 days is too much for me on day 1. I get insomnia on that night and a strong headache (I rarely get headaches) which as far as I have read, is due to a large drop in estrogen levels in the brain. This would mean it is working but too high a dose, no? The benefits I get are better energy, significantly higher libido (from near zero to lowish) and better sleep after day 1/2, presumably when the circulating levels have dropped a bit.

So it seems that as my body is weak it struggles to cope with this dose. Also perhaps my thyroid presumably being low is converting too much of topical application to estrogen? Anyway, I think I would do better on smaller doses. I think I have an old bottle of empty mitolipin kicking around somewhere @haidut would transfering 1 part pansterone and 1 part vodka (???) to this bottle result in ~0.65mg of both DHEA+PREG or is the dropper a different size?

Also, I have to squeeze the bottle really hard to get a drop. Is this by design or am I accidently somehow getting more than 1 drops worth when I do this?

 

[Wagner83]

Did you try it sublingually?

 

[SB4]

Did you try it sublingually?

Sort of, just a drop to the gums with no added water or anything

 

[haidut]

I found something 'white' stacked in under my toco/mct Pansterone's bottle.
tried to shake it but it didnt worked. Is it ok to use it just as usual?

Probably precipitated pregnenolone. It has very low solubility and a drop in temps can make some of it precipitate. I would just shake and use as usual.

 

[haidut]

To preface this I have quite bad CFS/POTS. I have experimented with lowish dose DHEA + PREG with good and bad effects. I have below reference range morning cortisol (1.74nmol/L [2.69-9.30]) and lowish DHEA.

I was taking too high a dose before so bought pansterone to try low dose. I am taking 1 drop in the morning every 5/6 days (still experimenting). I find oral to work better than topical.

Anyway I think that at even 1mg every 6 days is too much for me on day 1. I get insomnia on that night and a strong headache (I rarely get headaches) which as far as I have read, is due to a large drop in estrogen levels in the brain. This would mean it is working but too high a dose, no? The benefits I get are better energy, significantly higher libido (from near zero to lowish) and better sleep after day 1/2, presumably when the circulating levels have dropped a bit.

So it seems that as my body is weak it struggles to cope with this dose. Also perhaps my thyroid presumably being low is converting too much of topical application to estrogen? Anyway, I think I would do better on smaller doses. I think I have an old bottle of empty mitolipin kicking around somewhere @haidut would transfering 1 part pansterone and 1 part vodka (???) to this bottle result in ~0.65mg of both DHEA+PREG or is the dropper a different size?

Also, I have to squeeze the bottle really hard to get a drop. Is this by design or am I accidently somehow getting more than 1 drops worth when I do this?

You can dilute it but you need to use stronger alcohol than vodka as the pregnenolone will precipitate with vodka. Ethanol 90% or higher should work.

 

[PeatInspired]

Oops... I just found out that dhea isn't recommended in pregnancy.

But I mixed 100mg into my 34ml bottle of progest-e when I first bought it and having been using 3 drops twice per day vaginally... (Peat recommended for pelvic organ prolapse).

But now I'm 14 weeks pregnant and I've still been taking it! Granted, the dose has been quite low per day... But I'm still panicking.

The rest of the internet makes it sound quite dangerous to take while pregnant.

Anyone know anything reassuring?

 

[PeatInspired]

Oops... I just found out that dhea isn't recommended in pregnancy.

But I mixed 100mg into my 34ml bottle of progest-e when I first bought it and having been using 3 drops twice per day vaginally... (Peat recommended for pelvic organ prolapse).

But now I'm 14 weeks pregnant and I've still been taking it! Granted, the dose has been quite low per day... But I'm still panicking.

The rest of the internet makes it sound quite dangerous to take while pregnant.

Anyone know anything reassuring?

Hah, nevermind- women who take dhea for fertility typically take 75mg per day, and I was taking waaaaay less- only micrograms per day. So I'm sure I'll be fine.

 

[haidut]

Oops... I just found out that dhea isn't recommended in pregnancy.

But I mixed 100mg into my 34ml bottle of progest-e when I first bought it and having been using 3 drops twice per day vaginally... (Peat recommended for pelvic organ prolapse).

But now I'm 14 weeks pregnant and I've still been taking it! Granted, the dose has been quite low per day... But I'm still panicking.

The rest of the internet makes it sound quite dangerous to take while pregnant.

Anyone know anything reassuring?

Progesterone is the pregnancy-maintaining hormone. As long as it is high enough you should be OK, however DHEA can turn into estrogen and thus negatively affect pregnancy. As long as the progesterone outweighs the DHEA estrogenic effects the net result should be positive but I would do a hormone panel just in case.

 

[haidut]

Hah, nevermind- women who take dhea for fertility typically take 75mg per day, and I was taking waaaaay less- only micrograms per day. So I'm sure I'll be fine.

A 75mg dose is highly unsafe (estrogenic) even for a non-pregnant woman and I would absolutely not even try that when pregnant. Unless the doctor says otherwise, I would not use more than 5mg while pregnant and always take it with progesterone. Btw, those fertility studies rarely used more than 25mg and some of them used as little as 3mg daily. Not sure where you saw reports on women taking 75mg for fertility but if they do then it is likely to have an opposite effect at that dose. Animal studies show that anything more than 15mg human equivalent dose of DHEA raise prolactin, and high prolactin is a major cause of infertility in women.