Oxidal - Liquid Redox Modulator

[johnwester130]

what is the best explanation for using niacinamide,

and avoiding NADG/NAD supplements ?

 

[Obi-wan]

As I mentioned in another MB thread I take both the fish tank dye and Oxidal together. The fish tank dye is 30% MB by solution or approx 15mg per drop. I like to take one drop of each in a glass of water and then supplement with a drop here and there of Oxidal throughout the day. Due to my condition I need more of an oxidative catalyst. I also take Niacinamide 3 times a day and B1 several times a day with aspirin. I agree with @haidut, this is THE best supplement to reinforce oxidative metabolism!

 

[johnwester130]

This needs one thing added to it

Nicotine

 

[Lee Simeon]

This needs one thing added to it

Nicotine

Why?

 

[johnwester130]

Why?

TIME #14: BIOHACKING "TIME" WITH METHYLENE BLUE - Living an Optimized Life - mentons nicotine

Dr. Jack Kruse

"A fluorophore (or fluorochrome, similarly to a chromophore) is a fluorescent chemical compound that can re-emit light upon light excitation.

Nicotine is a fluorophore protein. NAD+/NADH couple in cytochrome 1 acts at 340 nm light. So if you over do it in the sun and use super physiologic doses of nicotine you can short out the first cytochrome and stimulate ROS. That will lead to many changes down stream like excessive ROS and RNS and it will destroy the lipids in mitochondria. "


actually the benzoic acid could be replaced

 

[johnwester130]

anyone know why it is used in IBS medicine

Uribel vs Hyophen

 

[johnwester130]

How safe is this drug ?

 

[Fractality]

TIME #14: BIOHACKING "TIME" WITH METHYLENE BLUE - Living an Optimized Life - mentons nicotine

Dr. Jack Kruse

"A fluorophore (or fluorochrome, similarly to a chromophore) is a fluorescent chemical compound that can re-emit light upon light excitation.

Nicotine is a fluorophore protein. NAD+/NADH couple in cytochrome 1 acts at 340 nm light. So if you over do it in the sun and use super physiologic doses of nicotine you can short out the first cytochrome and stimulate ROS. That will lead to many changes down stream like excessive ROS and RNS and it will destroy the lipids in mitochondria. "


actually the benzoic acid could be replaced

Is destroying the lipids in the mitochondria a good idea?

 

[johnwester130]

Is destroying the lipids in the mitochondria a good idea?

only in excess

 

[johnwester130]

Is destroying the lipids in the mitochondria a good idea?

". So if you over do it in the sun and use super physiologic doses of nicotine"

so too much sun and too high a dosage is bad for you

 

[haidut]

actually the benzoic acid could be replaced

Nope, the benzoic acid is crucial for Oxidal's effects. Benzoic acid, under the influence of electron withdrawing agents (like MB) gets converted into the powerful ortho-benzoquinone, which William Koch thought was THE principal anti-cancer chemical available naturally, better even than his C2O2 formulation. Look at this thread and do a Ctrl+F for "ortho".
Dr. William Frederich Koch USA/Brazil, Drs. Erich & Dieter Reinstorff, Germany - Continued Research

 

[ThinkPerceive]

Interesting thread. I thought the study showing benzoic acid to have uncoupling properties only at low doses - and NOT at higher doses - was intriguing. Have you considering using BHT in some way for a similar product? The same study showed effects very similar to benzoic acid in terms of uncoupling. Could one use both?

Since I've only recently placed a large-ish order, I may DYI this with my own ingredients. Besides, I know that I can take massive amounts of MB with zero problems (basically no effects at all), so might increase that while keeping the BA to just a couple mg. Maybe include some BHT because, why not...

 

[haidut]

Interesting thread. I thought the study showing benzoic acid to have uncoupling properties only at low doses - and NOT at higher doses - was intriguing. Have you considering using BHT in some way for a similar product? The same study showed effects very similar to benzoic acid in terms of uncoupling. Could one use both?

Since I've only recently placed a large-ish order, I may DYI this with my own ingredients. Besides, I know that I can take massive amounts of MB with zero problems (basically no effects at all), so might increase that while keeping the BA to just a couple mg. Maybe include some BHT because, why not...

BHT is estrogenic and anti-thyroid, not unlike BPA/BPS from plastic.
Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca(2+) pumps. - PubMed - NCBI

 

[ThinkPerceive]

BHT is estrogenic and anti-thyroid

Well, that's a good reason to avoid it!

 

[alywest]

I just wanted to say that I have started taking Oxidal at night before bed (2 drops topically) and it seems to be the magic elixir to help me sleep like a baby through the night. I take other things, too, but this seems to be the missing piece that was needed. When I took it during the day I got sleepy (perhaps a sign that my liver is still healing?) But my sleep has been amazing. I've never slept this well. It's like chick hatching out of the egg when I wake up in the morning or during the night when my kids wake me up. I don't wake up spontaneously since taking this. I am going to up the dose to three drops tonite to see if that causes any changes, although I'm not sure why I would do that since the two drops is working so well. Thank you @haidut!

 

[ddjd]

I just wanted to say that I have started taking Oxidal at night before bed (2 drops topically) and it seems to be the magic elixir to help me sleep like a baby through the night. I take other things, too, but this seems to be the missing piece that was needed. When I took it during the day I got sleepy (perhaps a sign that my liver is still healing?) But my sleep has been amazing. I've never slept this well. It's like chick hatching out of the egg when I wake up in the morning or during the night when my kids wake me up. I don't wake up spontaneously since taking this. I am going to up the dose to three drops tonite to see if that causes any changes, although I'm not sure why I would do that since the two drops is working so well. Thank you @haidut!

I'm so jealous. It has the opposite effect on me. @haidut any idea why I get insomnia from MB

 

[alywest]

I'm so jealous. It has the opposite effect on me. @haidut any idea why I get insomnia from MB

Some other supplements I take that may have a synergistic effect: t3, t4 (taken at night), lisuride (3 or 4 drops), cypro, progesterone

 

[Wagner83]

This is either too liquid or the dropper is too large, very difficult to get only one drop out of it (and not have an other one run down the dropper or stain the fingers). Also it's possible that there's too much mb per drop but then it's easy to dilute.

 

[haidut]

I'm so jealous. It has the opposite effect on me. @haidut any idea why I get insomnia from MB

You could be taking too much. In some people MB seems to raise serotonin pretty easily and that drives up adrenaline and cortisol.

 

[haidut]

This is either too liquid or the dropper is too large, very difficult to get only one drop out of it (and not have an other one run down the dropper or stain the fingers). Also it's possible that there's too much mb per drop but then it's easy to dilute.

Well, it is basically pure liquid with some "color" in it. Probably as liquid as SolBan and Energin. Unlike the steroid supplements, which are more viscous or the ones using tocopherols, this is one should be handled carefully to avoid oversqueezing. I have not seen other reports on people having issues with this supplement and the dropper, so I would just try to squeeze more gently.