Organ Extracts Stimulate Respiration Like Methylene Blue (MB)

[haidut]

In support of Ray's views of using organ extracts for therapeutic purposes. This study is from the 1930 and at the time they probably did not know about the existence of the thyroid hormone. What the study does is state that most organs, but especially liver and kidney, contained a "respiration enzyme" very similar to MB.

http://www.ncbi.nlm.nih.gov/pmc/article ... df/683.pdf

"...It is shown in this paper that aqueous extracts of various organs, especially liver, act in the same way as methylene blue. The respiration of erythrocytes induced by an organ extract is not altered in the presence of carbon monoxide. The content of this respiratory supplement in extracts of organs varies according to the organ: liver and kidney show the best effect; muscle, brain, and blood serum the least."

Perhaps more importantly, the study also states the following:

"...Only a damaged respiration could be improved by methylene blue, this dye acting as a substitute for the destroyed respiration enzyme."

"...FIC. 4. Shows that methylene blue increases the respiration only in presence of glucose (H) whereas it has no influence in absence of sugar (X). When sugar is added after the methylene blue has been in contact with the blood corpuscles for 2 hours, subsequent addition of sugar induces no respiration. The arrow shows the time of addition of glucose."

This matches the more recent studies posted by @Such_Saturation on MB having a toxicity threshold and also requiring glucose to increase cell respiration. It also matches the study on tumors I just posted in another thread, saying that MB is beneficial mostly to tumor cells since they are the ones that have damaged respiration.

 

[Such_Saturation]

Been going after that Ye Olde Time research lately I see

 

[haidut]

Been going after that Ye Olde Time research lately I see

Lol, I guess it would be hard to find recent studies on organ extracts. Not much interest in such cheap, rustic methods or improving health.
Actually, I was searching for studies on MB and metabolism on PubMed and imply followed the search results to the end, so some of them went back to early 20th century.

 

[Such_Saturation]

Not much interest in such cheap, rustic methods or improving health.

Yes, how barbaric!

 

[aguilaroja]

In support of Ray's views of using organ extracts for therapeutic purposes. This study..from ... 1930 state that most organs, but especially liver and kidney, contained a "respiration enzyme" very similar to MB.
http://www.ncbi.nlm.nih.gov/pmc/article ... /683.pdf...

Dr. Peat has repeatedly mentioned the work of Leonell Strong, an influential researcher in past decades. Strong is remembered among recent researchers for developing inbred strains of mice for cancer research.

In one study IIRC, Strong showed that a one time application of liver/nucleoside extract produced a tumor-suppressing effect that peaked numerous mouse generations later (e.g. great, great grandchild mice).

http://onlinelibrary.wiley.com/doi/10.3 ... 9.1.54/pdf
"He [LC Strong] followed up this theory..., focusing on a liver extract that significantly altered the growth rate of tumors when injected into cancerous mice. The effective components of this liver proved to be nucleosides... More than 70 per cent of mice treated with these non-toxic nucleosides have completely regressed spontaneous cancers of the mammary gland."

"Dr. Strong continued his work with liver extract, and the component nucleoside, finding the surprising result that tumor regression seemed to be transmissible through generations when the extract was injected into a pregnant or nursing mouse of a single generation."

 

[paymanz]

post 73942 Shows that methylene blue increases the respiration only in presence of glucose (H) whereas it has no influence in absence of sugar (X). When sugar is added after the methylene blue has been in contact with the blood corpuscles for 2 hours, subsequent addition of sugar induces no respiration

what about fructose?it has same interaction with MB?

 

[haidut]

what about fructose?it has same interaction with MB?

Not sure, but since it will get metabolized mostly into glucose it is probably also going to interact indirectly.

 

[milkboi]

This might explain why MB did nothing positive for me on a low carb diet.