Order Effects Of Combined Strength And Endurance Training On IGFBP3

[Elephanto]

Order effects of combined strength and endurance training on testosterone, cortisol, growth hormone, and IGF-1 binding protein 3 in concurrently tr... - PubMed - NCBI

Fourteen men (mean ± SD: 24.7 ± 5.1 years) were randomly divided into 2 groups: endurance training followed by strength (ES, n = 7) and strength training followed by endurance (SE, n = 7).

A significant interaction between exercise order and time was only found in the IGFBP-3 levels (p = 0.022).

The testosterone and IGFBP-3 concentrations significantly increased in the ES group after the exercise trainings (57.7 ± 35.1%, p = 0.013 and 17.0 ± 15.5%, p = 0.032, respectively) but did not change significantly in the SE group (15.5 ± 36.6%, p = 0.527 and -4.2 ± 13.9%, p = 0.421, respectively).

In conclusion, these results suggest that immediately postexercise testosterone and IGFPB-3 responses are significantly increased only after the ES order.

Small sample but still interesting because similar results are found in other larger studies on aerobic training and IGFBP3 (a gene that prevents male hair loss).

So IGFBP3 and testosterone only increase with endurance (cardio) training followed by muscle training, but not muscle training followed by endurance training. This is explained by this study :

IGFBP-3, a sensitive marker of physical training and overtraining. - PubMed - NCBI

there was a fall (of up to 25%) in IGFBP-3 levels after the match in the more fatigued subjects compared to an increase (of up to 40%) in fit subjects.

So we see that cardio training within the limits of one's capacity has a beneficial effect on IGFBP3, while exceeding it has a negative effect. This calls to progressive and cautious increments of efforts when training, until one has adapted to higher loads.

 

[paymanz]

Good info,thanks.

 

[Hans]

Not sure if this has been posted before. IGFBP3 was more suppressed in the morning and didn't increase in the same magnitude in response to morning training as to evening training.

"A time-of-day related elevation in serum IGFBP-3 (AM: 3274.9 ± 345.2, PM: 3605.1 ± 367.5, p = 0.032) was also evident."
The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential