Tristan Loscha
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- Dec 18, 2018
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DHA is greatly increased in patients with defective sperm.
Sci-Hub | Fatty acid composition of human spermatozoa and seminal plasma levels of oxidative stress biomarkers in subfertile males. Prostaglandins, Leukotrienes and Essential Fatty Acids, 77(2), 117–121 | 10.1016/j.plefa.2007.08.003
"Our data confirm the results obtained by Calamera et al. [13], who observed that sperm from normozoospermic individuals have lower unsaturated fatty acid content than sperm from asthenozoospermic individuals. They also assayed superoxide dismutase (SOD) content of spermatozoa which is increased in normozoospermic individuals. Calamera et al. therefore, concluded that spermatozoa from normozoospermic samples are less susceptible to reactive oxygen species (ROS)-induced peroxidative damages.
Ollero et al. reported that there is a net decrease in unsaturated fatty acid content, especially DHA, content and a concomitant decrease in saturated fatty acid content during the process of sperm maturation [3]. They concluded that one important physiological consequence of DHA removal from human sperm membrane during the process of sperm maturation is to decrease the susceptibility of sperm to lipid peroxidation.
We can conclude that spermatozoa from pathological samples may contain high levels of polyunsaturated fatty acids. On the other hand, these patients may contain low levels of antioxidant systems in their seminal plasma. Therefore, spermatozoa from pathological samples are more susceptible to ROS-induced peroxidative damage."
View attachment 13594
..of interest is also the fact of higher fat-amounts in the defective sperms in general.All have increasing Fat-counts,
especially Polyunsaturated ones.