I wonder why one mentioned this somatostatin analog called Octreotide.
It's main purpose is lowering GH/IGF-1 but it also has lot of beneficial effects.
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
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pubmed.ncbi.nlm.nih.gov
It's main purpose is lowering GH/IGF-1 but it also has lot of beneficial effects.
Effect of 4 weeks of octreotide treatment on prolactin, thyroid stimulating hormone and thyroid hormones in acromegalic patients. A double blind placebo-controlled cross-over study - PubMed
We aimed to test the hypothesis, that octreotide has a suppressive effect on unstimulated and TRH-stimulated PRL levels in both normo- and hyperprolactinaemic acromegalic patients, and besides to evaluate the effect of octreotide on unstimulated TSH and thyroid hormones. The present study is a...
pubmed.ncbi.nlm.nih.gov
Inhibition of recombinant human growth hormone-induced and prolactin-induced activation of neutrophils by octreotide - PubMed
Growth hormone, prolactin and somatostatin are polypeptide hormones of the neuroendocrine and peripheral nervous systems. In vitro, these have opposing effects on cells of the immune system. We compared the effects of these peptides on activation of neutrophils using a recombinant preparation of...
pubmed.ncbi.nlm.nih.gov
Octreotide inhibition of flushing and colonic motor dysfunction in carcinoid syndrome - PubMed
Octreotide ameliorates gut motor dysfunctions that characterize carcinoid diarrhea; the potential role of specific antagonism of serotonin, substance P, and vasoactive intestinal polypeptide alone or in combination with agents that inhibit their release in carcinoid diarrhea deserves further study.
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Octreotide inhibition of serotonin-induced ileal chloride secretion - PubMed
Octreotide (SMS, synthetic miniature somatostatin) effectively alleviates the secretory diarrhea of the malignant carcinoid syndrome. Although SMS inhibits tumor release of serotonin (5HT) and other bioactive agents, it also inhibits the diarrhea in patients who continue to exhibit elevated...
pubmed.ncbi.nlm.nih.gov
TSH-secreting pituitary adenoma: benefits of pre-operative octreotide - PubMed
The differential diagnosis of the syndrome of inappropriate TSH secretion is non-thyroidal illness, medications, assay interference due to heterophilic antibodies, thyroid hormone resistance and TSH-secreting pituitary adenoma.TRH stimulation test and triiodothyronine suppression test assist in...
pubmed.ncbi.nlm.nih.gov
Short-term preoperative octreotide treatment for TSH-secreting pituitary adenoma - PubMed
Preoperative control of hyperthyroidism in patients with TSH-secreting pituitary adenomas (TSHoma) may avoid perioperative thyroid storm. Perioperative administration of octreotide may control hyperthyroidism, as well as shrink tumor size. The effects of preoperative octreotide treatment were...
pubmed.ncbi.nlm.nih.gov
