Obesity-Related Cancers Increasing In The US

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"The CDC report finds that about 630,000 people in the U.S. were diagnosed with a cancer associated with overweight and obesity in 2014, the most recent data available. Excluding colorectal cancer, incidence rates increased significantly among those ages 20 to 74.

The rates of obesity-related cancers, not including colorectal cancer, increased by 7 percent between 2005 and 2014. The rates of non-obesity related cancers declined during that time.

Screening for colorectal cancer may have led to fewer incidence. Colorectal cancer rates declined in all age groups except in those ages 20 to 49.

Overall, the rate of new cancer cases has decreased since the 1990s, but increases in overweight- and obesity-related cancers are likely slowing this progress.

The CDC report pulled incidence data for the 13 cancers that International Agency for Research on Cancer (IARC) identifies as overweight- and obesity-related. AICR research links overweight and obesity to 11 cancers, including post-menopausal breast, colorectal and endometrial.

Body fat is a metabolically active organ and how it may promote cancer is an active area of research. Fat cells could lead to high levels of hormones that fuel certain cancers and produce substances that lead to chronic inflammation.

Multilevel approaches to comprehensive cancer control that include evidence-based interventions to address healthy weight and other cancer risk factors might help lower the burden of cancer and other chronic diseases, the authors conclude."


"Abstract

Background: Overweight and obesity are associated with increased risk of at least 13 different types of cancer.

Methods: Data from the United States Cancer Statistics for 2014 were used to assess incidence rates, and data from 2005 to 2014 were used to assess trends for cancers associated with overweight and obesity (adenocarcinoma of the esophagus; cancers of the breast [in postmenopausal women], colon and rectum, endometrium, gallbladder, gastric cardia, kidney, liver, ovary, pancreas, and thyroid; meningioma; and multiple myeloma) by sex, age, race/ethnicity, state, geographic region, and cancer site. Because screening for colorectal cancer can reduce colorectal cancer incidence through detection of precancerous polyps before they become cancerous, trends with and without colorectal cancer were analyzed.

Results: In 2014, approximately 631,000 persons in the United States received a diagnosis of a cancer associated with overweight and obesity, representing 40% of all cancers diagnosed. Overweight- and obesity-related cancer incidence rates were higher among older persons (ages ≥50 years) than younger persons; higher among females than males; and higher among non-Hispanic black and non-Hispanic white adults compared with other groups. Incidence rates for overweight- and obesity-related cancers during 2005–2014 varied by age, cancer site, and state. Excluding colorectal cancer, incidence rates increased significantly among persons aged 20–74 years; decreased among those aged ≥75 years; increased in 32 states; and were stable in 16 states and the District of Columbia.

Conclusions: The burden of overweight- and obesity-related cancer is high in the United States. Incidence rates of overweight- and obesity-related cancers except colorectal cancer have increased in some age groups and states.

Implications for Public Health Practice: The burden of overweight- and obesity-related cancers might be reduced through efforts to prevent and control overweight and obesity. Comprehensive cancer control strategies, including use of evidence-based interventions to promote healthy weight, could help decrease the incidence of these cancers in the United States."


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