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Brain catecholamines, serotonin and their metabolites in mice selected for low (MGL) and high (MGH) blood magnesium levels. - PubMed - NCBI
Magnes Res. 1995 Mar;8(1):5-9.
Brain catecholamines, serotonin and their metabolites in mice selected for low (MGL) and high (MGH) blood magnesium levels.
Amyard N1, Leyris A, Monier C, Francès H, Boulu RG, Henrotte JG.
"Noradrenaline levels were significantly higher (P < or = 0.001) in MGL than in MGH and Swiss mice : DOPAC levels were lower (P < or = 0.001) in MGL than in MGH and Swiss. Little or no differences were found for these variables between MGH and Swiss mice. MGL and MGH animals had similar brain dopamine, HVA and serotonin contents. These results suggest that the mere selection for genetic traits inducing low blood magnesium levels increases the synthesis of noradrenaline or decreases its catabolism. The above data together with the higher urinary noradrenalin excretion previously observed in the MGL line might account for the higher sensitivity and/or reactivity of MGL animals to stress."
Magnes Res. 1995 Mar;8(1):5-9.
Brain catecholamines, serotonin and their metabolites in mice selected for low (MGL) and high (MGH) blood magnesium levels.
Amyard N1, Leyris A, Monier C, Francès H, Boulu RG, Henrotte JG.
"Noradrenaline levels were significantly higher (P < or = 0.001) in MGL than in MGH and Swiss mice : DOPAC levels were lower (P < or = 0.001) in MGL than in MGH and Swiss. Little or no differences were found for these variables between MGH and Swiss mice. MGL and MGH animals had similar brain dopamine, HVA and serotonin contents. These results suggest that the mere selection for genetic traits inducing low blood magnesium levels increases the synthesis of noradrenaline or decreases its catabolism. The above data together with the higher urinary noradrenalin excretion previously observed in the MGL line might account for the higher sensitivity and/or reactivity of MGL animals to stress."
